Linoleic acid-derived metabolites constitute the majority of oxylipins in the rat pup brain and stimulate axonal growth in primary rat cortical neuron-glia co-cultures in a sex-dependent manner.

Hennebelle, Marie; Morgan, Rhianna K; Sethi, Sunjay; Zhang, Zhichao; Chen, Hao; Grodzki, Ana Cristina; Lein, Pamela J; Taha, Ameer Y

Hennebelle, Marie; Morgan, Rhianna K; Sethi, Sunjay; Zhang, Zhichao; Chen, Hao; Grodzki, Ana Cristina; Lein, Pamela J; Taha, Ameer Y.

Afiliação

Hennebelle M; Department of Food Science and Technology, College of Agriculture and Environmental Sciences, University of California, Davis, California, USA.
Morgan RK; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, California, USA.
Sethi S; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, California, USA.
Zhang Z; Department of Food Science and Technology, College of Agriculture and Environmental Sciences, University of California, Davis, California, USA.
Chen H; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, California, USA.
Grodzki AC; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, California, USA.
Lein PJ; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, California, USA.
Taha AY; Department of Food Science and Technology, College of Agriculture and Environmental Sciences, University of California, Davis, California, USA.

J Neurochem ; 152(2): 195-207, 2020 01.

Article em En | MEDLINE | ID: mdl-31283837

Assuntos

Axônios/metabolismo; Ácido Linoleico/administração & dosagem; Neuroglia/metabolismo; Neurônios/metabolismo; Oxilipinas/metabolismo; Caracteres Sexuais; Animais; Animais Recém-Nascidos; Axônios/química; Axônios/efeitos dos fármacos; Córtex Cerebral/química; Córtex Cerebral/efeitos dos fármacos; Córtex Cerebral/metabolismo; Técnicas de Cocultura; Feminino; Masculino; Neuroglia/química; Neuroglia/efeitos dos fármacos; Neurônios/química; Neurônios/efeitos dos fármacos; Oxilipinas/análise; Gravidez; Ratos; Ratos Sprague-Dawley

Palavras-chave

OXLAMs; fatty acids; neuronal morphogenesis; oxylipins

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Pregnancy Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Pregnancy Idioma: En Ano de publicação: 2020 Tipo de documento: Article