Cinnamaldehyde enhances apoptotic effect of oxaliplatin and reverses epithelial-mesenchymal transition and stemnness in hypoxic colorectal cancer cells.

Wu, Cun-En; Zhuang, Yu-Wen; Zhou, Jin-Yong; Liu, Shen-Lin; Wang, Rui-Ping; Shu, Peng

Wu, Cun-En; Zhuang, Yu-Wen; Zhou, Jin-Yong; Liu, Shen-Lin; Wang, Rui-Ping; Shu, Peng.

Afiliação

Wu CE; Department of Oncology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China.
Zhuang YW; Department of Oncology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China; Jinling Hospital Department of Integrated Traditional and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210002,
Zhou JY; Department of Oncology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China.
Liu SL; Department of Oncology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China.
Wang RP; Department of Oncology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China. Electronic address: wrp61@163.com.
Shu P; Department of Oncology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China. Electronic address: shupengsp@163.com.

Exp Cell Res ; 383(1): 111500, 2019 10 01.

Article em En | MEDLINE | ID: mdl-31306656

Assuntos

Acroleína/análogos & derivados; Apoptose/efeitos dos fármacos; Neoplasias Colorretais/tratamento farmacológico; Resistencia a Medicamentos Antineoplásicos/efeitos dos fármacos; Transição Epitelial-Mesenquimal/efeitos dos fármacos; Células-Tronco Neoplásicas/efeitos dos fármacos; Oxaliplatina/farmacologia; Acroleína/farmacologia; Animais; Antineoplásicos/farmacologia; Antineoplásicos Fitogênicos/farmacologia; Movimento Celular; Proliferação de Células; Neoplasias Colorretais/metabolismo; Neoplasias Colorretais/patologia; Feminino; Humanos; Hipóxia/fisiopatologia; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Células-Tronco Neoplásicas/metabolismo; Células-Tronco Neoplásicas/patologia; Células Tumorais Cultivadas; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

Cinnamaldehyde; Colorectal cancer; Epithelial-mesenchymal transition; Hypoxia; Oxaliplatin; Stemnness

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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