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Stereoelectronic Effects in Ligand Design: Enantioselective Rhodium-Catalyzed Hydrogenation of Aliphatic Cyclic Tetrasubstituted Enamides and Concise Synthesis of (R)-Tofacitinib.
Li, Chengxi; Wan, Feng; Chen, Yuan; Peng, Henian; Tang, Wenjun; Yu, Shu; McWilliams, J Christopher; Mustakis, Jason; Samp, Lacey; Maguire, Robert J.
Afiliação
  • Li C; State Key Laboratory of Bio-Organic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, 345 Ling Ling Road, Shanghai, 200032, China.
  • Wan F; State Key Laboratory of Bio-Organic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, 345 Ling Ling Road, Shanghai, 200032, China.
  • Chen Y; State Key Laboratory of Bio-Organic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, 345 Ling Ling Road, Shanghai, 200032, China.
  • Peng H; State Key Laboratory of Bio-Organic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, 345 Ling Ling Road, Shanghai, 200032, China.
  • Tang W; State Key Laboratory of Bio-Organic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, 345 Ling Ling Road, Shanghai, 200032, China.
  • Yu S; Chemical Research and Development, Pfizer Global R&D, Eastern Point Road, Groton, CT, 06340, USA.
  • McWilliams JC; Chemical Research and Development, Pfizer Global R&D, Eastern Point Road, Groton, CT, 06340, USA.
  • Mustakis J; Chemical Research and Development, Pfizer Global R&D, Eastern Point Road, Groton, CT, 06340, USA.
  • Samp L; Chemical Research and Development, Pfizer Global R&D, Eastern Point Road, Groton, CT, 06340, USA.
  • Maguire RJ; Chemical Research and Applied Synthetic Technologies, Pfizer Global R&D, Eastern Point Road, Groton, CT, 06340, USA.
Angew Chem Int Ed Engl ; 58(38): 13573-13583, 2019 09 16.
Article em En | MEDLINE | ID: mdl-31343811
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article