Blastocyst activation engenders transcriptome reprogram affecting X-chromosome reactivation and inflammatory trigger of implantation.

He, Bo; Zhang, Hangxiao; Wang, Jianqi; Liu, Mengying; Sun, Yang; Guo, Chuanhui; Lu, Jinhua; Wang, Haibin; Kong, Shuangbo

He, Bo; Zhang, Hangxiao; Wang, Jianqi; Liu, Mengying; Sun, Yang; Guo, Chuanhui; Lu, Jinhua; Wang, Haibin; Kong, Shuangbo.

Afiliação

He B; Reproductive Medical Center, The First Affiliated Hospital of Xiamen University, 361003 Xiamen, Fujian, People's Republic of China.
Zhang H; Fujian Provincial Key Laboratory of Reproductive Health Research, School of Medicine Xiamen University, 361102 Xiamen, Fujian, People's Republic of China.
Wang J; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, 100101 Beijing, People's Republic of China.
Liu M; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, 100101 Beijing, People's Republic of China.
Sun Y; Basic Forestry and Proteomics Research Center, College of Forestry, Fujian Agriculture and Forestry University, 350002 Fuzhou, Fujian, People's Republic of China.
Guo C; Fujian Provincial Key Laboratory of Reproductive Health Research, School of Medicine Xiamen University, 361102 Xiamen, Fujian, People's Republic of China.
Lu J; Fujian Provincial Key Laboratory of Reproductive Health Research, School of Medicine Xiamen University, 361102 Xiamen, Fujian, People's Republic of China.
Wang H; Reproductive Medical Center, The First Affiliated Hospital of Xiamen University, 361003 Xiamen, Fujian, People's Republic of China.
Kong S; Fujian Provincial Key Laboratory of Reproductive Health Research, School of Medicine Xiamen University, 361102 Xiamen, Fujian, People's Republic of China.

Proc Natl Acad Sci U S A ; 116(33): 16621-16630, 2019 08 13.

Article em En | MEDLINE | ID: mdl-31346081

Assuntos

Blastocisto/metabolismo; Implantação do Embrião/genética; Transcriptoma/genética; Cromossomo X/genética; Animais; Blastocisto/citologia; Calgranulina B/genética; Calgranulina B/metabolismo; Proliferação de Células/genética; Ectoderma/metabolismo; Ectoderma/ultraestrutura; Endométrio/patologia; Feminino; Regulação da Expressão Gênica no Desenvolvimento; Inflamação/patologia; Camundongos; Fatores de Tempo; Fator de Necrose Tumoral alfa/metabolismo; Regulação para Cima/genética

Palavras-chave

X-chromosome reactivation; blastocyst diapause and reactivation; embryo implantation; proinflammatory body; transcriptome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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