Early Scanning of Nascent Polypeptides inside the Ribosomal Tunnel by NAC.

Gamerdinger, Martin; Kobayashi, Kan; Wallisch, Annalena; Kreft, Stefan G; Sailer, Carolin; Schlömer, Renate; Sachs, Nadine; Jomaa, Ahmad; Stengel, Florian; Ban, Nenad; Deuerling, Elke

Gamerdinger, Martin; Kobayashi, Kan; Wallisch, Annalena; Kreft, Stefan G; Sailer, Carolin; Schlömer, Renate; Sachs, Nadine; Jomaa, Ahmad; Stengel, Florian; Ban, Nenad; Deuerling, Elke.

Afiliação

Gamerdinger M; Department of Biology, Molecular Microbiology, University of Konstanz, 78457 Konstanz, Germany. Electronic address: martin.gamerdinger@uni-konstanz.de.
Kobayashi K; Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland.
Wallisch A; Department of Biology, Molecular Microbiology, University of Konstanz, 78457 Konstanz, Germany.
Kreft SG; Department of Biology, Molecular Microbiology, University of Konstanz, 78457 Konstanz, Germany.
Sailer C; Department of Biology, University of Konstanz, 78457 Konstanz, Germany.
Schlömer R; Department of Biology, Molecular Microbiology, University of Konstanz, 78457 Konstanz, Germany.
Sachs N; Department of Biology, Molecular Microbiology, University of Konstanz, 78457 Konstanz, Germany.
Jomaa A; Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland.
Stengel F; Department of Biology, University of Konstanz, 78457 Konstanz, Germany.
Ban N; Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland. Electronic address: ban@mol.biol.ethz.ch.
Deuerling E; Department of Biology, Molecular Microbiology, University of Konstanz, 78457 Konstanz, Germany. Electronic address: elke.deuerling@uni-konstanz.de.

Mol Cell ; 75(5): 996-1006.e8, 2019 09 05.

Article em En | MEDLINE | ID: mdl-31377116

Assuntos

Proteínas de Caenorhabditis elegans/biossíntese; Caenorhabditis elegans/metabolismo; Retículo Endoplasmático/metabolismo; Biossíntese de Proteínas; Ribossomos/metabolismo; Canais de Translocação SEC/metabolismo; Animais; Caenorhabditis elegans/genética; Proteínas de Caenorhabditis elegans/genética; Retículo Endoplasmático/genética; Humanos; Ribossomos/genética; Canais de Translocação SEC/genética; Saccharomyces cerevisiae

Palavras-chave

ER targeting; NAC; RAC; SRP; Sec61; chaperone; nascent chain; nascent polypeptide-associated complex; protein biogenesis; ribosome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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