[Research Progress on Immune Mechanism of Immune Thrombocytopenia--Review].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
; 27(4): 1321-1324, 2019 Aug.
Article
em Zh
| MEDLINE
| ID: mdl-31418400
ABSTRACT
AbstractããImmune thrombocytopenia (ITP) is an acquired autoimmune hemorrhagic disease, although the ITP pathogenesis is completely unknown, but in terms of the current view, the immune tolerance is main reason for the onset of ITP. In recent years, more and more immune cell subsets, cytokines and the new approacher were found to be closely related with the ITP, such as saliva acid, B cell activating factor, dysfunction of regulatory B cells and Th1/Th2 balance drift, CD4+ CD25+ T cell function defect, IL-23/Th17 pathway regulation, etc., In this paper, the latest research progress on the immune pathogenesis of ITP are reviewed, so as to provide theoretical basis and research direction for further understanding the pathogenesis of ITP.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2019
Tipo de documento:
Article