Muscle Toxicity of Drugs: When Drugs Turn Physiology into Pathophysiology.

Janssen, Lando; Allard, Neeltje A E; Saris, Christiaan G J; Keijer, Jaap; Hopman, Maria T E; Timmers, Silvie

Janssen, Lando; Allard, Neeltje A E; Saris, Christiaan G J; Keijer, Jaap; Hopman, Maria T E; Timmers, Silvie.

Afiliação

Janssen L; Departments of Physiology, Hematology, and Neurology, Radboud University Medical Center, Nijmegen, The Netherlands; and Human and Animal Physiology, Wageningen University & Research, Wageningen, The Netherlands.
Allard NAE; Departments of Physiology, Hematology, and Neurology, Radboud University Medical Center, Nijmegen, The Netherlands; and Human and Animal Physiology, Wageningen University & Research, Wageningen, The Netherlands.
Saris CGJ; Departments of Physiology, Hematology, and Neurology, Radboud University Medical Center, Nijmegen, The Netherlands; and Human and Animal Physiology, Wageningen University & Research, Wageningen, The Netherlands.
Keijer J; Departments of Physiology, Hematology, and Neurology, Radboud University Medical Center, Nijmegen, The Netherlands; and Human and Animal Physiology, Wageningen University & Research, Wageningen, The Netherlands.
Hopman MTE; Departments of Physiology, Hematology, and Neurology, Radboud University Medical Center, Nijmegen, The Netherlands; and Human and Animal Physiology, Wageningen University & Research, Wageningen, The Netherlands.
Timmers S; Departments of Physiology, Hematology, and Neurology, Radboud University Medical Center, Nijmegen, The Netherlands; and Human and Animal Physiology, Wageningen University & Research, Wageningen, The Netherlands.

Physiol Rev ; 100(2): 633-672, 2020 04 01.

Article em En | MEDLINE | ID: mdl-31751166

Assuntos

Inibidores de Hidroximetilglutaril-CoA Redutases/efeitos adversos; Músculo Esquelético/efeitos dos fármacos; Doenças Musculares/induzido quimicamente; Animais; Humanos; Músculo Esquelético/patologia; Músculo Esquelético/fisiopatologia; Doenças Musculares/epidemiologia; Doenças Musculares/fisiopatologia; Doenças Musculares/terapia; Miotoxicidade; Valor Preditivo dos Testes; Prognóstico; Fatores de Risco

Palavras-chave

drug-induced myopathy; muscle toxicity; statin myopathy; statins

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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