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Aß43-producing PS1 FAD mutants cause altered substrate interactions and respond to γ-secretase modulation.
Trambauer, Johannes; Rodríguez Sarmiento, Rosa María; Fukumori, Akio; Feederle, Regina; Baumann, Karlheinz; Steiner, Harald.
Afiliação
  • Trambauer J; Biomedical Center (BMC), Metabolic Biochemistry, Ludwig-Maximilians-University, Munich, Germany.
  • Rodríguez Sarmiento RM; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Fukumori A; Department of Aging Neurobiology, National Center for Geriatrics and Gerontology, Obu, Japan.
  • Feederle R; Department of Mental Health Promotion, Osaka University Graduate School of Medicine, Toyonaka, Japan.
  • Baumann K; Institute for Diabetes and Obesity, Monoclonal Antibody Core Facility, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.
  • Steiner H; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
EMBO Rep ; 21(1): e47996, 2020 01 07.
Article em En | MEDLINE | ID: mdl-31762188
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article