IgE pyroglobulinemia in multiple myeloma.
Clin Chim Acta
; 176(2): 151-6, 1988 Aug 31.
Article
em En
| MEDLINE
| ID: mdl-3180463
ABSTRACT
A new case of IgE/K myeloma in a 38-year-old male is described. The clinical course, bone marrow picture and serum electrophoretic pattern were typical of multiple myeloma. Heating of the serum at 56 degrees C induced an irreversible gel formation or pyroglobulin that was isolated and proved to be identical to the IgE paraprotein, by biochemical and immunochemical methods. The thermoprecipitability was abolished by treatment with urea, sodium dodecyl sulphate and neutral salts and not inhibited by sugars, alcohols, 2-beta-mercaptoethanol and guanidine HCl. The association of an IgE myeloma protein with a pyroglobulin is a finding not previously reported in a myeloma of this class.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article