Vasorelaxant effects of Crataegus pentagyna: Links with arginase inhibition and phenolic profile.

Bujor, Alexandra; Miron, Anca; Luca, Simon Vlad; Skalicka-Wozniak, Krystyna; Silion, Mihaela; Trifan, Adriana; Girard, Corine; Demougeot, Céline; Totoson, Perle

Bujor, Alexandra; Miron, Anca; Luca, Simon Vlad; Skalicka-Wozniak, Krystyna; Silion, Mihaela; Trifan, Adriana; Girard, Corine; Demougeot, Céline; Totoson, Perle.

Afiliação

Bujor A; Department of Pharmacognosy, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Street, 700115, Iasi, Romania; PEPITE EA 4267, FHU INCREASE, University Bourgogne Franche-Comté, 19 rue Ambroise Paré, F-25030, Besançon, France. Electronic address: alexandra.m.bujor@umfiasi.ro.
Miron A; Department of Pharmacognosy, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Street, 700115, Iasi, Romania. Electronic address: anca.miron@umfiasi.ro.
Luca SV; Department of Pharmacognosy, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Street, 700115, Iasi, Romania; Biothermodynamics, TUM School of Life and Food Sciences Weihenstephan, Technical University of Munich, Maximus-von-Imhof-Forum 2, 85354, Freising, Germany. Electronic add
Skalicka-Wozniak K; Department of Pharmacognosy with Medicinal Plant Unit, Medical University of Lublin, Chodzki 1, 20-093, Lublin, Poland. Electronic address: kskalicka@pharmacognosy.org.
Silion M; Petru Poni Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487, Iasi, Romania. Electronic address: silion.mihaela@icmpp.ro.
Trifan A; Department of Pharmacognosy, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Street, 700115, Iasi, Romania. Electronic address: adriana.trifan@umfiasi.ro.
Girard C; PEPITE EA 4267, FHU INCREASE, University Bourgogne Franche-Comté, 19 rue Ambroise Paré, F-25030, Besançon, France. Electronic address: corine.girard@univ-fcomte.fr.
Demougeot C; PEPITE EA 4267, FHU INCREASE, University Bourgogne Franche-Comté, 19 rue Ambroise Paré, F-25030, Besançon, France. Electronic address: cdemouge@univ-fcomte.fr.
Totoson P; PEPITE EA 4267, FHU INCREASE, University Bourgogne Franche-Comté, 19 rue Ambroise Paré, F-25030, Besançon, France. Electronic address: perle.totoson@univ-fcomte.fr.

J Ethnopharmacol ; 252: 112559, 2020 Apr 24.

Article em En | MEDLINE | ID: mdl-31935497

Assuntos

Aorta Torácica/efeitos dos fármacos; Arginase/antagonistas & inibidores; Extratos Vegetais/farmacologia; Polifenóis/farmacologia; Vasodilatadores/farmacologia; Animais; Aorta Torácica/fisiologia; Cálcio/fisiologia; Crataegus; Endotélio Vascular/efeitos dos fármacos; Endotélio Vascular/fisiologia; Flores; Frutas; Masculino; Folhas de Planta; Canais de Potássio/fisiologia; Ratos Sprague-Dawley

Palavras-chave

Aortic rings; Arginase inhibition; Caffeic acid (PubChem CID: 689043); Chlorogenic acid (PubChem CID: 1794427); Citric acid (PubChem CID: 311); Crataegus pentagyna Waldst. et Kit. ex Willd.; Epicatechin (PubChem CID: 1203); Neochlorogenic acid (PubChem CID: 5280633); Nor-NOHA, Nω-hydroxy-nor-arginine (PubChem CID: 446124); Polyphenolic compounds; Quercetin (PubChem CID: 5280343); Rutin (PubChem CID: 5280805); Vasorelaxation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article