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Involved Site Radiation Therapy in Adult Lymphomas: An Overview of International Lymphoma Radiation Oncology Group Guidelines.
Wirth, Andrew; Mikhaeel, N George; Aleman, Berthe M P; Pinnix, Chelsea C; Constine, Louis S; Ricardi, Umberto; Illidge, Tim M; Eich, Hans Theodor; Hoppe, Bradford S; Dabaja, Bouthaina; Ng, Andrea K; Kirova, Youlia; Berthelsen, Anne Kiil; Dieckmann, Karin; Yahalom, Joachim; Specht, Lena.
Afiliação
  • Wirth A; Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria, Australia. Electronic address: andrew.wirth@petermac.org.
  • Mikhaeel NG; Guy's & St. Thomas' NHS Trust, and School of Cancer and Pharmaceutical Sciences, King's College London, United Kingdom.
  • Aleman BMP; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Pinnix CC; Department of Radiation Oncology, Hematologic Malignancies Section, University of Texas MD Anderson Cancer, Houston, Texas.
  • Constine LS; Department of Radiation Oncology, The Judy DiMarzo Cancer Survivorship Program, James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York.
  • Ricardi U; Department of Oncology, University of Turin.
  • Illidge TM; Division of Cancer Sciences, University of Manchester, National Institute of Health Biomedical Research Centre, Manchester Cancer Research Centre, Christie NHS Foundation Trust.
  • Eich HT; Department of Radiation Oncology, University of Muenster, Albert-Schweitzer, Muenster, Germany.
  • Hoppe BS; Mayo Clinic Florida, Jacksonville, Florida.
  • Dabaja B; Department of Radiation Oncology, University of Texas MD Anderson Cancer, International Lymphoma Radiation Oncology Group, Houston, Texas.
  • Ng AK; Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center.
  • Kirova Y; Department of Radiation Oncology Institut Curie, Paris, France.
  • Berthelsen AK; Department of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet and University of Copenhagen, Denmark; Department of Oncology, Rigshospitalet, Denmark.
  • Dieckmann K; Department of Radiooncology, Medical University Vienna, Austria.
  • Yahalom J; Memorial Sloan-Kettering Cancer Center, New York; Lymphoma Disease Management Team; Weill Cornell School of Medicine.
  • Specht L; Department of Clinical Oncology, Rigshospitalet, University of Copenhagen, Denmark.
Int J Radiat Oncol Biol Phys ; 107(5): 909-933, 2020 08 01.
Article em En | MEDLINE | ID: mdl-32272184
Involved node radiation therapy for lymphoma was introduced with the aim of using the smallest effective treatment volume, individualized to the patient's disease distribution, to avoid the potentially unnecessary normal tissue exposure and toxicity risks associated with traditional involved field radiation therapy. The successful implementation of involved node radiation therapy requires optimal imaging and precise coregistration of baseline imaging with the radiation therapy planning computed tomography scan. Limitations of baseline imaging, changes in patient position, and anatomic changes after chemotherapy may make this difficult in routine practice. Involved site radiation therapy (ISRT) was introduced by the International Lymphoma Radiation Oncology Group as a slightly larger treated volume, intended to allow for commonly encountered uncertainties. In addition to imaging considerations, the optimal ISRT treatment volume also depends on disease histology, stage, nodal or extranodal location, and the type and efficacy of systemic therapy, which in turn influence the distribution of macroscopic and potential subclinical disease. This article presents a systematic overview of ISRT, updating key evidence and highlighting differences in the application of ISRT across the lymphoma clinical spectrum.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Guideline / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Guideline / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article