Clinical potential of introducing next-generation sequencing in patients at relapse of acute myeloid leukemia.

Flach, Johanna; Shumilov, Evgenii; Wiedemann, Gertrud; Porret, Naomi; Shakhanova, Inna; Bürki, Susanne; Legros, Myriam; Joncourt, Raphael; Pabst, Thomas; Bacher, Ulrike

Flach, Johanna; Shumilov, Evgenii; Wiedemann, Gertrud; Porret, Naomi; Shakhanova, Inna; Bürki, Susanne; Legros, Myriam; Joncourt, Raphael; Pabst, Thomas; Bacher, Ulrike.

Afiliação

Flach J; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Mannheim, Germany.
Shumilov E; Department of Hematology and Medical Oncology, University Medicine Göttingen (UMG), Göttingen, Germany.
Wiedemann G; University Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, Bern, Switzerland.
Porret N; Center of Laboratory Medicine (ZLM)/University Institute of Clinical Chemistry, Inselspital, Bern University Hospital, Bern, Switzerland.
Shakhanova I; University Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, Bern, Switzerland.
Bürki S; Center of Laboratory Medicine (ZLM)/University Institute of Clinical Chemistry, Inselspital, Bern University Hospital, Bern, Switzerland.
Legros M; Department of Nephrology and Rheumatology, University Medicine Göttingen (UMG), Göttingen, Germany.
Joncourt R; Department of Medical Oncology, Inselspital, Bern University Hospital, Bern, Switzerland.
Pabst T; Center of Laboratory Medicine (ZLM)/University Institute of Clinical Chemistry, Inselspital, Bern University Hospital, Bern, Switzerland.
Bacher U; University Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, Bern, Switzerland.

Hematol Oncol ; 38(4): 425-431, 2020 Oct.

Article em En | MEDLINE | ID: mdl-32306411

Assuntos

Antineoplásicos/uso terapêutico; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Leucemia Mieloide Aguda/tratamento farmacológico; Mutação; Proteínas de Neoplasias/antagonistas & inibidores; Proteínas de Neoplasias/genética; Recidiva Local de Neoplasia/tratamento farmacológico; Humanos; Leucemia Mieloide Aguda/genética; Leucemia Mieloide Aguda/patologia; Terapia de Alvo Molecular; Recidiva Local de Neoplasia/genética; Recidiva Local de Neoplasia/patologia

Palavras-chave

acute myeloid leukemia (AML); minimal residual disease (MRD); next-generation sequencing (NGS); relapse

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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