Mass Spectrometry-Based Proteomic Characterization of Cutaneous Melanoma Ectosomes Reveals the Presence of Cancer-Related Molecules.

Surman, Magdalena; Kedracka-Krok, Sylwia; Hoja-Lukowicz, Dorota; Jankowska, Urszula; Drozdz, Anna; Stepien, Ewa L; Przybylo, Malgorzata

Surman, Magdalena; Kedracka-Krok, Sylwia; Hoja-Lukowicz, Dorota; Jankowska, Urszula; Drozdz, Anna; Stepien, Ewa L; Przybylo, Malgorzata.

Afiliação

Surman M; Department of Glycoconjugate Biochemistry, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, 30-387 Kraków, Poland.
Kedracka-Krok S; Department of Physical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Kraków, Poland.
Hoja-Lukowicz D; Department of Glycoconjugate Biochemistry, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, 30-387 Kraków, Poland.
Jankowska U; Proteomics and Mass Spectrometry Core Facility, Malopolska Centre of Biotechnology, Jagiellonian University, 30-387 Kraków, Poland.
Drozdz A; Department of Medical Physics, M. Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 30-348 Kraków, Poland.
Stepien EL; Department of Medical Physics, M. Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 30-348 Kraków, Poland.
Przybylo M; Department of Glycoconjugate Biochemistry, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, 30-387 Kraków, Poland.

Int J Mol Sci ; 21(8)2020 Apr 22.

Article em En | MEDLINE | ID: mdl-32331267

Assuntos

Micropartículas Derivadas de Células/metabolismo; Exossomos/metabolismo; Melanoma/metabolismo; Proteômica; Neoplasias Cutâneas/metabolismo; Espectrometria de Massas em Tandem; Biomarcadores; Linhagem Celular Tumoral; Cromatografia Líquida; Biologia Computacional/métodos; Perfilação da Expressão Gênica; Ontologia Genética; Humanos; Melanoma/genética; Neoplasias Cutâneas/genética; Melanoma Maligno Cutâneo

Palavras-chave

biomarkers; cutaneous melanoma; ectosomes; extracellular vesicles; invasion; metastasis; proteomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article