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Identification of type 2 diabetes loci in 433,540 East Asian individuals.
Spracklen, Cassandra N; Horikoshi, Momoko; Kim, Young Jin; Lin, Kuang; Bragg, Fiona; Moon, Sanghoon; Suzuki, Ken; Tam, Claudia H T; Tabara, Yasuharu; Kwak, Soo-Heon; Takeuchi, Fumihiko; Long, Jirong; Lim, Victor J Y; Chai, Jin-Fang; Chen, Chien-Hsiun; Nakatochi, Masahiro; Yao, Jie; Choi, Hyeok Sun; Iyengar, Apoorva K; Perrin, Hannah J; Brotman, Sarah M; van de Bunt, Martijn; Gloyn, Anna L; Below, Jennifer E; Boehnke, Michael; Bowden, Donald W; Chambers, John C; Mahajan, Anubha; McCarthy, Mark I; Ng, Maggie C Y; Petty, Lauren E; Zhang, Weihua; Morris, Andrew P; Adair, Linda S; Akiyama, Masato; Bian, Zheng; Chan, Juliana C N; Chang, Li-Ching; Chee, Miao-Li; Chen, Yii-Der Ida; Chen, Yuan-Tsong; Chen, Zhengming; Chuang, Lee-Ming; Du, Shufa; Gordon-Larsen, Penny; Gross, Myron; Guo, Xiuqing; Guo, Yu; Han, Sohee; Howard, Annie-Green.
Afiliação
  • Spracklen CN; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Horikoshi M; Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA, USA.
  • Kim YJ; Laboratory for Endocrinology, Metabolism and Kidney Diseases, RIKEN Centre for Integrative Medical Sciences, Yokohama, Japan.
  • Lin K; Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, Republic of Korea.
  • Bragg F; Nuffield Department of Population Health, University of Oxford, Oxford, UK.
  • Moon S; Nuffield Department of Population Health, University of Oxford, Oxford, UK.
  • Suzuki K; Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, Republic of Korea.
  • Tam CHT; Laboratory for Endocrinology, Metabolism and Kidney Diseases, RIKEN Centre for Integrative Medical Sciences, Yokohama, Japan.
  • Tabara Y; Laboratory for Statistical and Translational Genetics, RIKEN Centre for Integrative Medical Sciences, Yokohama, Japan.
  • Kwak SH; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Takeuchi F; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Long J; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
  • Lim VJY; Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Chai JF; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Chen CH; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
  • Nakatochi M; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
  • Yao J; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Choi HS; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
  • Iyengar AK; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
  • Perrin HJ; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
  • Brotman SM; Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • van de Bunt M; The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
  • Gloyn AL; Department of Pediatrics, UCLA School of Medicine, Harbor-UCLA Medical Center, Torrance, CA, USA.
  • Below JE; Biomedical Science, Hallym University, Chuncheon, South Korea.
  • Boehnke M; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Bowden DW; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Chambers JC; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Mahajan A; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
  • McCarthy MI; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Ng MCY; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
  • Petty LE; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Zhang W; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.
  • Morris AP; Stanford University, Stanford, CA, USA.
  • Adair LS; Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Akiyama M; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Bian Z; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
  • Chan JCN; Center for Genomics and Personalized Medicine Research, Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Chang LC; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Chee ML; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
  • Chen YI; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
  • Chen YT; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, London, UK.
  • Chen Z; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.
  • Chuang LM; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.
  • Du S; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
  • Gordon-Larsen P; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Gross M; Genentech, South San Francisco, CA, USA.
  • Guo X; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
  • Guo Y; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Han S; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.
  • Howard AG; Genentech, South San Francisco, CA, USA.
Nature ; 582(7811): 240-245, 2020 06.
Article em En | MEDLINE | ID: mdl-32499647
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Female / Humans / Male País/Região como assunto: Asia / Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Female / Humans / Male País/Região como assunto: Asia / Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article