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A polysaccharide extract from the medicinal plant Maidong inhibits the IKK-NF-κB pathway and IL-1ß-induced islet inflammation and increases insulin secretion.
Mao, Dandan; Tian, Xiao Yu; Mao, Di; Hung, Sze Wan; Wang, Chi Chiu; Lau, Clara Bik San; Lee, Heung Man; Wong, Chun Kwok; Chow, Elaine; Ming, Xing; Cao, Huanyi; Ma, Ronald C; Chan, Paul K S; Kong, Alice P S; Li, Joshua J X; Rutter, Guy A; Tam, Wing Hung; Chan, Juliana C N.
Afiliação
  • Mao D; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Tian XY; School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, China.
  • Mao D; Department of Obstetrics and Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Hung SW; Department of Obstetrics and Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Wang CC; Department of Obstetrics and Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Lau CBS; Institute of Chinese Medicine and State Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants, Chinese University of Hong Kong, Hong Kong, China.
  • Lee HM; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Wong CK; Department of Chemical Pathology, Chinese University of Hong Kong, Hong Kong, China.
  • Chow E; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Ming X; Phase 1 Clinical Trial Centre, Chinese University of Hong Kong, Hong Kong, China.
  • Cao H; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Ma RC; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Chan PKS; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Kong APS; Hong Kong Institute of Diabetes and Obesity, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Li JJX; Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Rutter GA; Department of Medical Microbiology, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Tam WH; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
  • Chan JCN; Hong Kong Institute of Diabetes and Obesity, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
J Biol Chem ; 295(36): 12573-12587, 2020 09 04.
Article em En | MEDLINE | ID: mdl-32605924
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article