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Five-Step Enantioselective Synthesis of Islatravir via Asymmetric Ketone Alkynylation and an Ozonolysis Cascade.
Patel, Niki R; Huffman, Mark A; Wang, Xiao; Ding, Bangwei; McLaughlin, Mark; Newman, Justin A; Andreani, Teresa; Maloney, Kevin M; Johnson, Heather C; Whittaker, Aaron M.
Afiliação
  • Patel NR; Department of Process Research and Development, MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.
  • Huffman MA; Department of Process Research and Development, MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.
  • Wang X; Department of Process Research and Development, MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.
  • Ding B; Department of Process Research and Development, MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.
  • McLaughlin M; Department of Process Research and Development, MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.
  • Newman JA; Department of Process Research and Development, MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.
  • Andreani T; Department of Process Research and Development, MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.
  • Maloney KM; Department of Process Research and Development, MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.
  • Johnson HC; Department of Process Research and Development, MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.
  • Whittaker AM; Department of Process Research and Development, MRL, Merck & Co., Inc., Rahway, NJ, 07065, USA.
Chemistry ; 26(62): 14118-14123, 2020 Nov 06.
Article em En | MEDLINE | ID: mdl-32710473
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article