Correction of serum potassium with sodium zirconium cyclosilicate in Japanese patients with hyperkalemia: a randomized, dose-response, phase 2/3 study.

Kashihara, Naoki; Nishio, Toshiki; Osonoi, Takeshi; Saka, Yosuke; Imasawa, Toshiyuki; Ohtake, Takayasu; Mizuno, Hiroshi; Shibagaki, Yugo; Kim, Hyosung; Yajima, Toshitaka; Sarai, Nobuaki

Kashihara, Naoki; Nishio, Toshiki; Osonoi, Takeshi; Saka, Yosuke; Imasawa, Toshiyuki; Ohtake, Takayasu; Mizuno, Hiroshi; Shibagaki, Yugo; Kim, Hyosung; Yajima, Toshitaka; Sarai, Nobuaki.

Afiliação

Kashihara N; Department of Nephrology and Hypertension, Kawasaki Medical School, Okayama, Japan.
Nishio T; Nephrology Dialysis Center, Kusatsu General Hospital, Shiga, Japan.
Osonoi T; Department of Internal Medicine, Nakakinen Clinic, Ibaraki, Japan.
Saka Y; Department of Nephrology, Kasugai Municipal Hospital, Aichi, Japan.
Imasawa T; Department of Nephrology, Chiba-Higashi Hospital, Chiba, Japan.
Ohtake T; Department of Nephrology, Shonan Kamakura General Hospital, Kanagawa, Japan.
Mizuno H; Department of Nephrology, Inage Hospital, Chiba, Japan.
Shibagaki Y; Division of Nephrology and Hypertension, St. Marianna University School of Medicine Hospital, Kanagawa, Japan.
Kim H; Research and Development, AstraZeneca K.K, 1-8-3, Marunouchi, Chiyoda-ku, Tokyo, 100-0005, Japan.
Yajima T; Research and Development, AstraZeneca K.K, 1-8-3, Marunouchi, Chiyoda-ku, Tokyo, 100-0005, Japan.
Sarai N; Research and Development, AstraZeneca K.K, 1-8-3, Marunouchi, Chiyoda-ku, Tokyo, 100-0005, Japan. nobuaki.sarai@astrazeneca.com.

Clin Exp Nephrol ; 24(12): 1144-1153, 2020 Dec.

Article em En | MEDLINE | ID: mdl-32779057

Assuntos

Quelantes/uso terapêutico; Hiperpotassemia/tratamento farmacológico; Potássio/sangue; Silicatos/uso terapêutico; Idoso; Idoso de 80 Anos ou mais; Biomarcadores/sangue; Quelantes/efeitos adversos; Método Duplo-Cego; Feminino; Humanos; Hiperpotassemia/sangue; Hiperpotassemia/diagnóstico; Japão; Masculino; Pessoa de Meia-Idade; Silicatos/efeitos adversos; Fatores de Tempo; Resultado do Tratamento

Palavras-chave

Hyperkalemia; Japan; Japanese; Sodium zirconium cyclosilicate

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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