Knockout of PRDX6 induces mitochondrial dysfunction and cell cycle arrest at G2/M in HepG2 hepatocarcinoma cells.

López-Grueso, María José; Lagal, Daniel José; García-Jiménez, Álvaro Fernando; Tarradas, Rosa María; Carmona-Hidalgo, Beatriz; Peinado, José; Requejo-Aguilar, Raquel; Bárcena, José Antonio; Padilla, Carmen Alicia

López-Grueso, María José; Lagal, Daniel José; García-Jiménez, Álvaro Fernando; Tarradas, Rosa María; Carmona-Hidalgo, Beatriz; Peinado, José; Requejo-Aguilar, Raquel; Bárcena, José Antonio; Padilla, Carmen Alicia.

Afiliação

López-Grueso MJ; Dept. of Biochemistry and Molecular Biology, University of Córdoba, Spain.
Lagal DJ; Dept. of Biochemistry and Molecular Biology, University of Córdoba, Spain.
García-Jiménez ÁF; Dept. of Biochemistry and Molecular Biology, University of Córdoba, Spain.
Tarradas RM; Dept. of Biochemistry and Molecular Biology, University of Córdoba, Spain.
Carmona-Hidalgo B; Dept. of Biochemistry and Molecular Biology, University of Córdoba, Spain.
Peinado J; Dept. of Biochemistry and Molecular Biology, University of Córdoba, Spain; Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Requejo-Aguilar R; Dept. of Biochemistry and Molecular Biology, University of Córdoba, Spain; Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Bárcena JA; Dept. of Biochemistry and Molecular Biology, University of Córdoba, Spain; Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain. Electronic address: ja.barcena@uco.es.
Padilla CA; Dept. of Biochemistry and Molecular Biology, University of Córdoba, Spain; Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.

Redox Biol ; 37: 101737, 2020 10.

Article em En | MEDLINE | ID: mdl-33035814

Assuntos

Pontos de Checagem do Ciclo Celular; Mitocôndrias; Peroxirredoxina VI; Proteínas Quinases Dependentes de 3-Fosfoinositídeo/metabolismo; Pontos de Checagem do Ciclo Celular/genética; Células Hep G2; Humanos; Mitocôndrias/genética; Mitocôndrias/metabolismo; Oxirredução; Peroxirredoxina VI/metabolismo; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

CRISPR-Cas9; Carbohydrate metabolism; Cell cycle; Glucose metabolism; Lipokines; Mitochondria; NRF2; PCNA; Peroxiredoxin 6; Proteomics; Redox proteome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article