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Model-Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin.
Sou, Tomás; Hansen, Jon; Liepinsh, Edgars; Backlund, Maria; Ercan, Onur; Grinberga, Solveiga; Cao, Sha; Giachou, Paraskevi; Petersson, Anna; Tomczak, Magdalena; Urbas, Malgorzata; Zabicka, Dorota; Vingsbo Lundberg, Carina; Hughes, Diarmaid; Hobbie, Sven N; Friberg, Lena E.
Afiliação
  • Sou T; Pharmacometrics, Department of Pharmacy, Uppsala University, Uppsala, Sweden.
  • Hansen J; Department of Bacteria, Parasites and Fungi, Statens Serum Institute, Copenhagen, Denmark.
  • Liepinsh E; Latvian Institute of Organic Synthesis, Riga, Latvia.
  • Backlund M; Department of Pharmacy, Uppsala University Drug Optimization and Pharmaceutical Profiling, Uppsala University, Uppsala, Sweden.
  • Ercan O; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
  • Grinberga S; Latvian Institute of Organic Synthesis, Riga, Latvia.
  • Cao S; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
  • Giachou P; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
  • Petersson A; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
  • Tomczak M; Department of Epidemiology and Clinical Microbiology, National Medicines Institute, Warsaw, Poland.
  • Urbas M; Department of Epidemiology and Clinical Microbiology, National Medicines Institute, Warsaw, Poland.
  • Zabicka D; Department of Epidemiology and Clinical Microbiology, National Medicines Institute, Warsaw, Poland.
  • Vingsbo Lundberg C; Department of Bacteria, Parasites and Fungi, Statens Serum Institute, Copenhagen, Denmark.
  • Hughes D; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
  • Hobbie SN; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.
  • Friberg LE; Pharmacometrics, Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Clin Pharmacol Ther ; 109(4): 1063-1073, 2021 04.
Article em En | MEDLINE | ID: mdl-33150591
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article