Overexpression of Macrophage-Inducible C-Type Lectin Mincle Aggravates Proinflammatory Responses to <i>Streptococcus pneumoniae</i> with Fatal Outcome in Mice.

Hollwedel, Femke D; Maus, Regina; Stolper, Jennifer; Khan, Ayesha; Stocker, Bridget L; Timmer, Mattie S M; Lu, Xiuyuan; Pich, Andreas; Welte, Tobias; Yamasaki, Sho; Maus, Ulrich A

Overexpression of Macrophage-Inducible C-Type Lectin Mincle Aggravates Proinflammatory Responses to Streptococcus pneumoniae with Fatal Outcome in Mice.

Hollwedel, Femke D; Maus, Regina; Stolper, Jennifer; Khan, Ayesha; Stocker, Bridget L; Timmer, Mattie S M; Lu, Xiuyuan; Pich, Andreas; Welte, Tobias; Yamasaki, Sho; Maus, Ulrich A.

Afiliação

Hollwedel FD; Division of Experimental Pneumology, Hannover Medical School, Hannover 30625, Germany.
Maus R; Division of Experimental Pneumology, Hannover Medical School, Hannover 30625, Germany.
Stolper J; Division of Experimental Pneumology, Hannover Medical School, Hannover 30625, Germany.
Khan A; School of Chemical and Physical Sciences, Victoria University of Wellington, Wellington 6140, New Zealand.
Stocker BL; School of Chemical and Physical Sciences, Victoria University of Wellington, Wellington 6140, New Zealand.
Timmer MSM; School of Chemical and Physical Sciences, Victoria University of Wellington, Wellington 6140, New Zealand.
Lu X; Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan.
Pich A; Institute of Toxicology and Core Facility Proteomics, Hannover Medical School, Hannover 30625, Germany.
Welte T; German Center for Lung Research, Partner Site Biomedical Research in Endstage and Obstructive Lung Disease Hannover, Hannover 30625, Germany; and.
Yamasaki S; Clinic for Pneumology, Hannover Medical School, Hannover 30625, Germany.
Maus UA; Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan.

J Immunol ; 205(12): 3390-3399, 2020 12 15.

Article em En | MEDLINE | ID: mdl-33158955

Assuntos

Lectinas Tipo C/imunologia; Macrófagos Alveolares/imunologia; Proteínas de Membrana/imunologia; Pneumonia Pneumocócica/imunologia; Streptococcus pneumoniae/imunologia; Animais; Inflamassomos/genética; Inflamassomos/imunologia; Interleucina-1beta/genética; Interleucina-1beta/imunologia; Lectinas Tipo C/genética; Macrófagos Alveolares/patologia; Proteínas de Membrana/genética; Camundongos; Camundongos Transgênicos; Proteína 3 que Contém Domínio de Pirina da Família NLR/genética; Proteína 3 que Contém Domínio de Pirina da Família NLR/imunologia; Pneumonia Pneumocócica/genética; Pneumonia Pneumocócica/patologia

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article