4-1BB costimulation promotes bystander activation of human CD8 T cells.

Reithofer, Manuel; Rosskopf, Sandra; Leitner, Judith; Battin, Claire; Bohle, Barbara; Steinberger, Peter; Jahn-Schmid, Beatrice

4-1BB costimulation promotes bystander activation of human CD8 T cells.

Reithofer, Manuel; Rosskopf, Sandra; Leitner, Judith; Battin, Claire; Bohle, Barbara; Steinberger, Peter; Jahn-Schmid, Beatrice.

Afiliação

Reithofer M; Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Rosskopf S; Division of Immune Receptors and T Cell Activation, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Leitner J; Division of Immune Receptors and T Cell Activation, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Battin C; Division of Immune Receptors and T Cell Activation, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Bohle B; Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Steinberger P; Division of Immune Receptors and T Cell Activation, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Jahn-Schmid B; Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

Eur J Immunol ; 51(3): 721-733, 2021 03.

Article em En | MEDLINE | ID: mdl-33180337

Assuntos

Linfócitos T CD8-Positivos/imunologia; Ativação Linfocitária/imunologia; Células Apresentadoras de Antígenos/imunologia; Linhagem Celular; Linhagem Celular Tumoral; Proliferação de Células/fisiologia; Genes MHC Classe I/imunologia; Humanos; Células K562; Células Matadoras Naturais/imunologia; Receptores do Ligante Indutor de Apoptose Relacionado a TNF/imunologia; Membro 7 da Superfamília de Receptores de Fatores de Necrose Tumoral/imunologia

Palavras-chave

Bystander activation; CD27; CD8; Costimulation agonist; T-cell costimulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article