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Impact of duration of untreated illness in bipolar I disorder (manic episodes) on clinical outcome, socioecnomic burden in Egyptian population.
Ahmed, Gellan K; Elbeh, Khalid; Khalifa, Hossam; Samaan, Maggi Raoof.
Afiliação
  • Ahmed GK; Department of Neurology and Psychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt; Department of Child & Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 8AF, UK. Electronic address: gillankaram@aun.edu.eg.
  • Elbeh K; Department of Neurology and Psychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt.
  • Khalifa H; Department of Neurology and Psychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt.
  • Samaan MR; Department of Child & Adolescent Psychiatry, Assiut mental health hospital, Assiut, Egypt.
Psychiatry Res ; 296: 113659, 2021 02.
Article em En | MEDLINE | ID: mdl-33360586
INTRODUCTION: Bipolar disorder (BD) is a serious and chronic mental illness that may result in disability. We evaluated effect of the duration of untreated of bipolar (DUB) (manic episodes) on clinical outcomes, including episode severity, residual symptoms, duration of hospitalization, and suicide attempts, and on socioeconomic status of patients. METHODS: A total of 216 participants who had bipolar I disorder (manic state) recruited from November 2017-December 2019 from an inpatient psychiatric unit. Patients divided into 2 groups based on DUB: Group A, with DUB < 4 months; and Group B, with DUB ≥4 months. All participants had evaluation for demographic and clinical features, Socioeconomic scale, Young mania rating scale (YMRS) at admission and discharge. RESULTS: Group A participants were more often male, urban residents, married, literate and educated, professionally employed. Group A had a younger age of onset, less duration of illness, less frequency of episode, less suicide attempts, less duration in hospital, high mean of socioeconomic, lower mean of YMRS at admission and discharge in compared to Group B. CONCLUSION: A longer DUB (manic episodes)was associated with negative clinical outcomes (more frequent episode, more symptoms severity, longer hospital admission, more suicide severity, more residual symptoms) and low socioeconomic state of patients with BDI (manic episodes).
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Limite: Adult / Humans / Male / Middle aged País/Região como assunto: Africa Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Limite: Adult / Humans / Male / Middle aged País/Região como assunto: Africa Idioma: En Ano de publicação: 2021 Tipo de documento: Article