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Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease.
Crawford, Andrew A; Bankier, Sean; Altmaier, Elisabeth; Barnes, Catriona L K; Clark, David W; Ermel, Raili; Friedrich, Nele; van der Harst, Pim; Joshi, Peter K; Karhunen, Ville; Lahti, Jari; Mahajan, Anubha; Mangino, Massimo; Nethander, Maria; Neumann, Alexander; Pietzner, Maik; Sukhavasi, Katyayani; Wang, Carol A; Bakker, Stephan J L; Bjorkegren, Johan L M; Campbell, Harry; Eriksson, Johan; Gieger, Christian; Hayward, Caroline; Jarvelin, Marjo-Riitta; McLachlan, Stela; Morris, Andrew P; Ohlsson, Claes; Pennell, Craig E; Price, Jackie; Rudan, Igor; Ruusalepp, Arno; Spector, Tim; Tiemeier, Henning; Völzke, Henry; Wilson, James F; Michoel, Tom; Timpson, Nicolas J; Smith, George Davey; Walker, Brian R.
Afiliação
  • Crawford AA; BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
  • Bankier S; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Altmaier E; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Barnes CLK; BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
  • Clark DW; Division of Genetics and Genomics, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
  • Ermel R; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
  • Friedrich N; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.
  • van der Harst P; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.
  • Joshi PK; Department of Cardiac Surgery, Tartu University Hospital, Tartu, Estonia.
  • Karhunen V; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475, Greifswald, Germany.
  • Lahti J; German Center for Cardiovascular Disease (DZHK e.V.), partner site Greifswald, 17475, Greifswald, Germany.
  • Mahajan A; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Mangino M; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, PO box 30.001, 9700 RB, The Netherlands.
  • Nethander M; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.
  • Neumann A; Department of Epidemiology and Biostatistics, Medical Research Council-Public Health England Centre for Environment and Health, Imperial College London, London, UK.
  • Pietzner M; Centre for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.
  • Sukhavasi K; Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.
  • Wang CA; Turku Institute of Advanced Studies, University of Turku, Turku, Finland.
  • Bakker SJL; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
  • Bjorkegren JLM; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Campbell H; Department of Twin Research and Genetic Epidemiology, King's College, Lambeth Palace Road, London, SE1 7EH, UK.
  • Eriksson J; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, UK.
  • Gieger C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Hayward C; Bioinformatics Core Facility, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Jarvelin MR; Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
  • McLachlan S; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada.
  • Morris AP; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475, Greifswald, Germany.
  • Ohlsson C; German Center for Cardiovascular Disease (DZHK e.V.), partner site Greifswald, 17475, Greifswald, Germany.
  • Pennell CE; Department of Cardiac Surgery, Tartu University Hospital, Tartu, Estonia.
  • Price J; School of Medicine and Public Health, Faculty of Medicine and Health, University of Newcastle, Newcastle, NSW, 2308, Australia.
  • Rudan I; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Ruusalepp A; Integrated Cardio Metabolic Centre, Department of Medicine, Karolinska Institutet, Karolinska Universitetssjukhuset, Huddinge, Sweden.
  • Spector T; Department of Genetics & Genomic Sciences, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Tiemeier H; Clinical Gene Networks AB, Stockholm, Sweden.
  • Völzke H; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.
  • Wilson JF; Folkhälsan Research Center, Helsinki, Finland.
  • Michoel T; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Timpson NJ; Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Helsinki, Singapore.
  • Smith GD; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Walker BR; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
J Hum Genet ; 66(6): 625-636, 2021 Jun.
Article em En | MEDLINE | ID: mdl-33469137

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article