Hemodynamic compromise in pulmonary embolism: "A tale of two ventricles".
Catheter Cardiovasc Interv
; 97(2): 299-300, 2021 02 01.
Article
em En
| MEDLINE
| ID: mdl-33587803
ABSTRACT
In acute pulmonary embolism (PE), low cardiac output (CO)-hypotension results from disparate ventricular conditions The left ventricle (LV) is under-filled and contracting vigorously, whereas the right ventricle (RV) is failing and dilated. The proximate cause of LV preload deprivation is thrombus-induced pulmonary vascular obstruction; abruptly increased pulmonary vascular resistance (PVR) induces acute RV systolic dysfunction which further compromises trans-pulmonary flow. "Escalation of Care" interventions (thrombolytics and aspiration thrombectomy) improve systemic hemodynamics by increasing LV preload delivery directly by reducing PVR and indirectly by relief of the strained failing RV.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Etiology_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article