GPA33 is expressed on multiple human blood cell types and distinguishes CD4<sup>+</sup> central memory T cells with and without effector function.

Opstelten, Rianne; Suwandi, Jessica S; Slot, Manon C; Morgana, Florencia; Scott, Andrew M; Laban, Sandra; Nikolic, Tatjana; Turksma, Annelies W; Kroeze, Anna; Voermans, Carlijn; Zwaginga, Jaap-Jan; Roep, Bart O; Amsen, Derk

GPA33 is expressed on multiple human blood cell types and distinguishes CD4⁺ central memory T cells with and without effector function.

Opstelten, Rianne; Suwandi, Jessica S; Slot, Manon C; Morgana, Florencia; Scott, Andrew M; Laban, Sandra; Nikolic, Tatjana; Turksma, Annelies W; Kroeze, Anna; Voermans, Carlijn; Zwaginga, Jaap-Jan; Roep, Bart O; Amsen, Derk.

Afiliação

Opstelten R; Department of Hematopoiesis and Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Suwandi JS; Immunomodulation and Regenerative Cell Therapy, Department of Internal Medicine, Leiden University Medical Center, Leiden, Netherlands.
Slot MC; Department of Hematopoiesis and Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Morgana F; Department of Hematopoiesis and Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Scott AM; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, and School of Cancer Medicine, La Trobe University, Melbourne, Australia.
Laban S; Immunomodulation and Regenerative Cell Therapy, Department of Internal Medicine, Leiden University Medical Center, Leiden, Netherlands.
Nikolic T; Immunomodulation and Regenerative Cell Therapy, Department of Internal Medicine, Leiden University Medical Center, Leiden, Netherlands.
Turksma AW; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Kroeze A; Department of Hematopoiesis and Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Voermans C; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Zwaginga JJ; Department of Hematopoiesis and Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Roep BO; Immunomodulation and Regenerative Cell Therapy, Department of Internal Medicine, Leiden University Medical Center, Leiden, Netherlands.
Amsen D; Sanquin Research, Center for Clinical Transfusion Research and Jon J van Rood Center for Clinical Transfusion Science, Leiden University Medical Center, Leiden, Netherlands.

Eur J Immunol ; 51(6): 1377-1389, 2021 06.

Article em En | MEDLINE | ID: mdl-33728639

Assuntos

Biomarcadores/metabolismo; Linfócitos T CD4-Positivos/imunologia; Leucócitos Mononucleares/imunologia; Glicoproteínas de Membrana/metabolismo; Subpopulações de Linfócitos T/imunologia; Linfócitos T Reguladores/imunologia; Diferenciação Celular; Linhagem da Célula; Separação Celular; Citometria de Fluxo; Células HEK293; Humanos; Imunidade Inata; Memória Imunológica; Glicoproteínas de Membrana/genética; Receptores CXCR5/metabolismo

Palavras-chave

CD4+ T cell differentiation; CyTOF; antibody therapy; flow cytometry; human glycoprotein A33

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article