Integration of single-cell and bulk RNA sequencing data reveals key cell types and regulators in traumatic brain injury.

Zheng, Rui-Zhe; Xing, Jin; Huang, Qiong; Yang, Xi-Tao; Zhao, Chang-Yi; Li, Xin-Yuan

Zheng, Rui-Zhe; Xing, Jin; Huang, Qiong; Yang, Xi-Tao; Zhao, Chang-Yi; Li, Xin-Yuan.

Afiliação

Zheng RZ; Department of Neurosurgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China.
Xing J; Department of Neurosurgery, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai 201399, China.
Huang Q; Department of Neurology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China.
Yang XT; Department of Neurosurgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Zhao CY; Department of Neurosurgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China.
Li XY; Department of Neurosurgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China.

Math Biosci Eng ; 18(2): 1201-1214, 2021 01 14.

Article em En | MEDLINE | ID: mdl-33757183

Assuntos

Lesões Encefálicas Traumáticas; RNA; Animais; Lesões Encefálicas Traumáticas/genética; Modelos Animais de Doenças; Células Endoteliais; Humanos; Camundongos; Camundongos Endogâmicos C57BL; Análise de Sequência de RNA

Palavras-chave

TYROBP causal network; cell-cell communication; microglia; single-cell RNA-seq; traumatic brain injury

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article