HAND transcription factors cooperatively specify the aorta and pulmonary trunk.

Vincentz, Joshua W; Firulli, Beth A; Toolan, Kevin P; Osterwalder, Marco; Pennacchio, Len A; Firulli, Anthony B

Vincentz, Joshua W; Firulli, Beth A; Toolan, Kevin P; Osterwalder, Marco; Pennacchio, Len A; Firulli, Anthony B.

Afiliação

Vincentz JW; Herman B Wells Center for Pediatric Research Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Indiana University School of Medicine, 1044 W. Walnut St., Indianapolis, IN, 46202-5225, USA. Electronic address: joshua.vincentz@regeneron.com.
Firulli BA; Herman B Wells Center for Pediatric Research Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Indiana University School of Medicine, 1044 W. Walnut St., Indianapolis, IN, 46202-5225, USA.
Toolan KP; Herman B Wells Center for Pediatric Research Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Indiana University School of Medicine, 1044 W. Walnut St., Indianapolis, IN, 46202-5225, USA.
Osterwalder M; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA; Department for BioMedical Research (DBMR), University of Bern, Murtenstrasse 35, 3008, Bern, Switzerland.
Pennacchio LA; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA; U.S. Department of Energy Joint Genome Institute, Berkeley, CA, 94720, USA; Comparative Biochemistry Program, University of California, Berkeley, CA, 94720, USA.
Firulli AB; Herman B Wells Center for Pediatric Research Department of Pediatrics, Anatomy, Biochemistry, and Medical and Molecular Genetics, Indiana University School of Medicine, 1044 W. Walnut St., Indianapolis, IN, 46202-5225, USA. Electronic address: tfirulli@iu.edu.

Dev Biol ; 476: 1-10, 2021 08.

Article em En | MEDLINE | ID: mdl-33757801

Assuntos

Fatores de Transcrição Hélice-Alça-Hélice Básicos/genética; Cardiopatias Congênitas/genética; Coração/embriologia; Animais; Aorta/embriologia; Fatores de Transcrição Hélice-Alça-Hélice Básicos/metabolismo; Débito Cardíaco/fisiologia; Movimento Celular/genética; Regulação da Expressão Gênica no Desenvolvimento/genética; Cardiopatias Congênitas/metabolismo; Proteínas de Homeodomínio/metabolismo; Camundongos; Camundongos Knockout; Miocárdio/metabolismo; Miócitos Cardíacos/metabolismo; Crista Neural/metabolismo; Fenótipo; Transdução de Sinais/genética; Fatores de Transcrição/genética

Palavras-chave

Cardiac neural crest; Cardiac outflow track; Congenital heart defects; HAND1; HAND2; Second heart field; Transcription; bHLH transcription factors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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