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Antibody responses to the BNT162b2 mRNA vaccine in individuals previously infected with SARS-CoV-2.
Ebinger, Joseph E; Fert-Bober, Justyna; Printsev, Ignat; Wu, Min; Sun, Nancy; Prostko, John C; Frias, Edwin C; Stewart, James L; Van Eyk, Jennifer E; Braun, Jonathan G; Cheng, Susan; Sobhani, Kimia.
Afiliação
  • Ebinger JE; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Fert-Bober J; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Printsev I; Advanced Clinical Biosystems Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Wu M; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Sun N; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Prostko JC; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Frias EC; Applied Research and Technology, Abbott Diagnostics, Abbott Park, IL, USA.
  • Stewart JL; Applied Research and Technology, Abbott Diagnostics, Abbott Park, IL, USA.
  • Van Eyk JE; Applied Research and Technology, Abbott Diagnostics, Abbott Park, IL, USA.
  • Braun JG; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Cheng S; Advanced Clinical Biosystems Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Sobhani K; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. jonathan.braun2@cshs.org.
Nat Med ; 27(6): 981-984, 2021 06.
Article em En | MEDLINE | ID: mdl-33795870
In a cohort of BNT162b2 (Pfizer-BioNTech) mRNA vaccine recipients (n = 1,090), we observed that spike-specific IgG antibody levels and ACE2 antibody binding inhibition responses elicited by a single vaccine dose in individuals with prior SARS-CoV-2 infection (n = 35) were similar to those seen after two doses of vaccine in individuals without prior infection (n = 228). Post-vaccine symptoms were more prominent for those with prior infection after the first dose, but symptomology was similar between groups after the second dose.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article