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Foot-and-mouth disease viruses of the O/ME-SA/Ind-2001e sublineage in Pakistan.
Jamal, Syed M; Khan, Salman; Knowles, Nick J; Wadsworth, Jemma; Hicks, Hayley M; Mioulet, Valérie; Bin-Tarif, Abdelghani; Ludi, Anna B; Shah, Syed Asad Ali; Abubakar, Muhammad; Manzoor, Shumaila; Afzal, Muhammad; Eschbaumer, Michael; King, Donald P; Belsham, Graham J.
Afiliação
  • Jamal SM; Department of Biotechnology, University of Malakand, Chakdara, Pakistan.
  • Khan S; Department of Biotechnology, University of Malakand, Chakdara, Pakistan.
  • Knowles NJ; FAO World Reference Laboratory for FMD (WRLFMD), The Pirbright Institute, Woking, UK.
  • Wadsworth J; FAO World Reference Laboratory for FMD (WRLFMD), The Pirbright Institute, Woking, UK.
  • Hicks HM; FAO World Reference Laboratory for FMD (WRLFMD), The Pirbright Institute, Woking, UK.
  • Mioulet V; FAO World Reference Laboratory for FMD (WRLFMD), The Pirbright Institute, Woking, UK.
  • Bin-Tarif A; FAO World Reference Laboratory for FMD (WRLFMD), The Pirbright Institute, Woking, UK.
  • Ludi AB; FAO World Reference Laboratory for FMD (WRLFMD), The Pirbright Institute, Woking, UK.
  • Shah SAA; Livestock and Dairy Development Department, Peshawar, Pakistan.
  • Abubakar M; National Veterinary Laboratories, Islamabad, Pakistan.
  • Manzoor S; The Project for Enhancement of Foot and Mouth Disease Control in Pakistan (OSRO/PAK/801/JPN), Food and Agriculture Organization of the United Nations, Islamabad, Pakistan.
  • Afzal M; The Project for Enhancement of Foot and Mouth Disease Control in Pakistan (OSRO/PAK/801/JPN), Food and Agriculture Organization of the United Nations, Islamabad, Pakistan.
  • Eschbaumer M; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
  • King DP; FAO World Reference Laboratory for FMD (WRLFMD), The Pirbright Institute, Woking, UK.
  • Belsham GJ; Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark.
Transbound Emerg Dis ; 68(6): 3126-3135, 2021 Nov.
Article em En | MEDLINE | ID: mdl-33915027
ABSTRACT
The presence of foot-and-mouth disease virus (FMDV) of the O/ME-SA/Ind-2001e sublineage within Pakistan was initially detected in two samples collected during 2019. Analysis of further serotype O FMDVs responsible for disease outbreaks in 2019-2020 in the country has now identified the spread of this sublineage to 10 districts within two separate provinces in North-Eastern and North-Western Pakistan. Phylogenetic analysis indicates that these viruses are closely related to those circulating in Bhutan, Nepal and India. The VP1 coding sequences of these viruses from Pakistan belong to three distinct clusters, which may indicate multiple introductions of this virus sublineage, although the routes of introduction are unknown. Vaccine matching studies against O1 Manisa, O 3039 and O TUR/5/2009 support the suitability of existing vaccine strains to control current field outbreaks, but further studies are warranted to monitor the spread and evolution of the O/ME-SA/Ind-2001e sublineage in the region. (145 words).
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals País/Região como assunto: Asia Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals País/Região como assunto: Asia Idioma: En Ano de publicação: 2021 Tipo de documento: Article