Evaluation of Selective COX-2 Inhibition and In Silico Study of Kuwanon Derivatives Isolated from <i>Morus alba</i>.

Baek, Seung-Hwa; Hwang, Sungbo; Park, Tamina; Kwon, Yoon-Ju; Cho, Myounglae; Park, Daeui

Evaluation of Selective COX-2 Inhibition and In Silico Study of Kuwanon Derivatives Isolated from Morus alba.

Baek, Seung-Hwa; Hwang, Sungbo; Park, Tamina; Kwon, Yoon-Ju; Cho, Myounglae; Park, Daeui.

Afiliação

Baek SH; Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon 34114, Korea.
Hwang S; Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon 34114, Korea.
Park T; Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon 34114, Korea.
Kwon YJ; Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon 34114, Korea.
Cho M; Department of Human and Environmental Toxicology, University of Science and Technology, Daejeon 34113, Korea.
Park D; National Institute for Korean Medicine Development, Gyeongsan 38540, Korea.

Int J Mol Sci ; 22(7)2021 Apr 01.

Article em En | MEDLINE | ID: mdl-33915826

Assuntos

Derivados de Benzeno/farmacologia; Inibidores de Ciclo-Oxigenase 2/isolamento & purificação; Flavonoides/farmacologia; Morus/química; Derivados de Benzeno/isolamento & purificação; Flavonoides/isolamento & purificação; Simulação de Acoplamento Molecular; Extratos Vegetais/química

Palavras-chave

cyclooxygenase inhibition assay; docking simulation; kuwanon A; quantum mechanics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article