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Autism-associated SHANK3 missense point mutations impact conformational fluctuations and protein turnover at synapses.
Bucher, Michael; Niebling, Stephan; Han, Yuhao; Molodenskiy, Dmitry; Hassani Nia, Fatemeh; Kreienkamp, Hans-Jürgen; Svergun, Dmitri; Kim, Eunjoon; Kostyukova, Alla S; Kreutz, Michael R; Mikhaylova, Marina.
Afiliação
  • Bucher M; AG Optobiology, Institute of Biology, Humboldt-University, Berlin, Germany.
  • Niebling S; DFG Emmy Noether Guest Group 'Neuronal Protein Transport', Institute for Molecular Neurogenetics, Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
  • Han Y; RG Neuroplasticity, Leibniz-Institute for Neurobiology (LIN), Magdeburg, Germany.
  • Molodenskiy D; Molecular Biophysics and High-Throughput Crystallization, European Molecular Biology Laboratory (EMBL), Hamburg, Germany.
  • Hassani Nia F; DFG Emmy Noether Guest Group 'Neuronal Protein Transport', Institute for Molecular Neurogenetics, Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
  • Kreienkamp HJ; Structural Cell Biology of Viruses, Centre for Structural Systems Biology (CSSB) and Leibniz Institute for Experimental Virology, Hamburg, Germany.
  • Svergun D; European Molecular Biology Laboratory (EMBL) Hamburg Unit, DESY, Hamburg, Germany.
  • Kim E; Institute of Human Genetics, Center for Obstetrics and Pediatrics, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
  • Kostyukova AS; Institute of Human Genetics, Center for Obstetrics and Pediatrics, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
  • Kreutz MR; European Molecular Biology Laboratory (EMBL) Hamburg Unit, DESY, Hamburg, Germany.
  • Mikhaylova M; Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Elife ; 102021 05 04.
Article em En | MEDLINE | ID: mdl-33945465
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article