DNA Damage Repair Inhibitor for Breast Cancer Treatment.

Min, Ahrum; Lee, Kyung-Hun; Im, Seock-Ah

Min, Ahrum; Lee, Kyung-Hun; Im, Seock-Ah.

Afiliação

Min A; Cancer Research Institute, Seoul National University, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea.
Lee KH; Department of Internal Medicine, Seoul National University Hospital, Cancer Research Institute, Seoul National University, Seoul, South Korea.
Im SA; Department of Internal Medicine, Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul National University, Seoul, South Korea. moisa@snu.ac.kr.

Adv Exp Med Biol ; 1187: 159-179, 2021.

Article em En | MEDLINE | ID: mdl-33983578

Assuntos

Neoplasias da Mama; Neoplasias Ovarianas; Neoplasias da Mama/tratamento farmacológico; Neoplasias da Mama/genética; Dano ao DNA; Reparo do DNA; Feminino; Humanos; Neoplasias Ovarianas/tratamento farmacológico; Inibidores de Poli(ADP-Ribose) Polimerases/farmacologia; Inibidores de Poli(ADP-Ribose) Polimerases/uso terapêutico

Palavras-chave

BRCAness; DNA damage repair; Homologous recombination deficiency; PARP inhibitor; Synthetic lethality

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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