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Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Wei, Pengcheng; Jordan, Kimberly R; Buhrman, Jonathan D; Lei, Jun; Deng, Hexiang; Marrack, Philippa; Dai, Shaodong; Kappler, John W; Slansky, Jill E; Yin, Lei.
Afiliação
  • Wei P; Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, 430072 Wuhan, China.
  • Jordan KR; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO 80206.
  • Buhrman JD; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO 80206.
  • Lei J; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
  • Deng H; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO 80206.
  • Marrack P; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
  • Dai S; Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, 430072 Wuhan, China.
  • Kappler JW; Key Laboratory of Biomedical Polymers, Ministry of Education, Institute for Advanced Studies, College of Chemistry and Molecular Sciences, Wuhan University, 430072 Wuhan, China.
  • Slansky JE; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO 80206.
  • Yin L; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
Proc Natl Acad Sci U S A ; 118(23)2021 06 08.
Article em En | MEDLINE | ID: mdl-34074778
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article