Discordance Between Immunohistochemistry and In Situ Hybridization to Detect HER2 Overexpression/Gene Amplification in Breast Cancer in the Modern Age: A Single Institution Experience and Pooled Literature Review Study.

Memon, Raima; Prieto Granada, Carlos N; Harada, Shuko; Winokur, Thomas; Reddy, Vishnu; Kahn, Andrea G; Siegal, Gene P; Wei, Shi

Memon, Raima; Prieto Granada, Carlos N; Harada, Shuko; Winokur, Thomas; Reddy, Vishnu; Kahn, Andrea G; Siegal, Gene P; Wei, Shi.

Afiliação

Memon R; Department of Pathology.
Prieto Granada CN; Department of Pathology.
Harada S; Department of Pathology; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL.
Winokur T; Department of Pathology.
Reddy V; Department of Pathology.
Kahn AG; Department of Pathology.
Siegal GP; Department of Pathology; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL.
Wei S; Department of Pathology; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL. Electronic address: swei@uabmc.edu.

Clin Breast Cancer ; 22(1): e123-e133, 2022 01.

Article em En | MEDLINE | ID: mdl-34120846

Assuntos

Neoplasias da Mama/metabolismo; Imuno-Histoquímica/normas; Hibridização In Situ/normas; Receptor ErbB-2/metabolismo; Biomarcadores Tumorais/metabolismo; Neoplasias da Mama/patologia; Erros de Diagnóstico; Feminino; Amplificação de Genes; Humanos; Hibridização in Situ Fluorescente/métodos; Variações Dependentes do Observador

Palavras-chave

HER2; amplification; breast cancer; discordance; overexpression

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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