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Preclinical metabolism and disposition of an orally bioavailable macrocyclic FXIa inhibitor.
Chacko, Silvi A; Yang, Wu; Wang, Yufeng; Tian, Yuan; Hong, Yang; Wallace, Michael; Wang, Bonnie; Ewing, William R; Luettgen, Joseph M; Shu, Yue-Zhong; Christopher, Lisa J.
Afiliação
  • Chacko SA; Department of Nonclinical Research and Development, Bristol Myers Squibb Pharmaceutical Research and Development, Princeton, NJ, USA.
  • Yang W; Discovery Chemistry, Bristol Myers Squibb Pharmaceutical Research and Development, Princeton, NJ, USA.
  • Wang Y; Discovery Chemistry, Bristol Myers Squibb Pharmaceutical Research and Development, Princeton, NJ, USA.
  • Tian Y; Discovery Chemistry, Bristol Myers Squibb Pharmaceutical Research and Development, Princeton, NJ, USA.
  • Hong Y; Discovery Chemistry, Bristol Myers Squibb Pharmaceutical Research and Development, Princeton, NJ, USA.
  • Wallace M; Discovery Chemistry, Bristol Myers Squibb Pharmaceutical Research and Development, Princeton, NJ, USA.
  • Wang B; Department of Nonclinical Research and Development, Bristol Myers Squibb Pharmaceutical Research and Development, Princeton, NJ, USA.
  • Ewing WR; Discovery Chemistry, Bristol Myers Squibb Pharmaceutical Research and Development, Princeton, NJ, USA.
  • Luettgen JM; Discovery Biology, Bristol Myers Squibb Pharmaceutical Research and Development, Princeton, NJ, USA.
  • Shu YZ; Department of Nonclinical Research and Development, Bristol Myers Squibb Pharmaceutical Research and Development, Princeton, NJ, USA.
  • Christopher LJ; Department of Nonclinical Research and Development, Bristol Myers Squibb Pharmaceutical Research and Development, Princeton, NJ, USA.
Xenobiotica ; 51(8): 933-948, 2021 Aug.
Article em En | MEDLINE | ID: mdl-34151691
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article