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NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.
Allouche, Jennifer; Rachmin, Inbal; Adhikari, Kaustubh; Pardo, Luba M; Lee, Ju Hee; McConnell, Alicia M; Kato, Shinichiro; Fan, Shaohua; Kawakami, Akinori; Suita, Yusuke; Wakamatsu, Kazumasa; Igras, Vivien; Zhang, Jianming; Navarro, Paula P; Lugo, Camila Makhlouta; Noonan, Haley R; Christie, Kathleen A; Itin, Kaspar; Mujahid, Nisma; Lo, Jennifer A; Won, Chong Hyun; Evans, Conor L; Weng, Qing Yu; Wang, Hequn; Osseiran, Sam; Lovas, Alyssa; Németh, István; Cozzio, Antonio; Navarini, Alexander A; Hsiao, Jennifer J; Nguyen, Nhu; Kemény, Lajos V; Iliopoulos, Othon; Berking, Carola; Ruzicka, Thomas; Gonzalez-José, Rolando; Bortolini, Maria-Cátira; Canizales-Quinteros, Samuel; Acuna-Alonso, Victor; Gallo, Carla; Poletti, Giovanni; Bedoya, Gabriel; Rothhammer, Francisco; Ito, Shosuke; Schiaffino, Maria Vittoria; Chao, Luke H; Kleinstiver, Benjamin P; Tishkoff, Sarah; Zon, Leonard I; Nijsten, Tamar.
Afiliação
  • Allouche J; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Rachmin I; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Adhikari K; School of Mathematics and Statistics, The Open University, Milton Keynes, MK7 6AA, UK; Department of Genetics, Evolution and Environment and UCL Genetics Institute, University College London, London WC1E 6BT, UK.
  • Pardo LM; Department of Dermatology, Erasmus Medical Center, 3015 Rotterdam, the Netherlands.
  • Lee JH; Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, 03722 Seoul, Korea.
  • McConnell AM; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and the Howard Hughes Medical Institute, Boston, MA 02115, USA.
  • Kato S; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA; Department of Immunology, Center for 5D Cell Dynamics, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
  • Fan S; State Key Laboratory of Genetic Engineering, Human Phenome Institute, School of Life Sciences, Fudan University, 200438 Shanghai, China.
  • Kawakami A; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Suita Y; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Wakamatsu K; Institute for Melanin Chemistry, Fujita Health University, Toyoake, Aichi 470-1192, Japan.
  • Igras V; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Zhang J; National Research Center for Translational Medicine (Shanghai), State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 200025 Shanghai, China.
  • Navarro PP; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Lugo CM; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Noonan HR; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and the Howard Hughes Medical Institute, Boston, MA 02115, USA.
  • Christie KA; Center for Genomic Medicine and Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.
  • Itin K; Department of Dermatology, University Hospital of Basel, 4031 Basel, Switzerland.
  • Mujahid N; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA; Boston University School of Medicine, Boston, MA 02118, USA; University of Utah, Department of Dermatology, Salt Lake City, UT 84132, USA.
  • Lo JA; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Won CH; Department of Dermatology, Asan Medical Center, Ulsan University College of Medicine, 05505 Seoul, Korea.
  • Evans CL; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Weng QY; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Wang H; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Osseiran S; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Lovas A; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Németh I; Department of Dermatology and Allergology, University of Szeged, 6720 Szeged, Hungary.
  • Cozzio A; Department of Dermatology, Venerology, and Allergology, Kantonsspital St. Gallen, 9007 St. Gallen, Switzerland.
  • Navarini AA; Department of Dermatology, University Hospital of Basel, 4031 Basel, Switzerland.
  • Hsiao JJ; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Nguyen N; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  • Kemény LV; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA; Department of Dermatology, Venereology, and Dermatooncology, Semmelweis University, 1085 Budapest, Hungary.
  • Iliopoulos O; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Berking C; Department of Dermatology, Universitätsklinikum Erlangen, Friedrich Alexander University Erlangen-Nürnberg, 91054, Erlangen, Germany.
  • Ruzicka T; Department of Dermatology and Allergy, University Hospital Munich, Ludwig Maximilian University, 80337 Munich, Germany.
  • Gonzalez-José R; Instituto Patagónico de Ciencias Sociales y Humanas-Centro Nacional Patagónico, CONICET, Puerto Madryn U912OACD, Argentina.
  • Bortolini MC; Departamento de Genética, Universidade Federal do Rio Grande do Sul, Porto Alegre 91501-970, Brazil.
  • Canizales-Quinteros S; Unidad de Genómica de Poblaciones Aplicada a la Salud, Facultad de Química, Universidad Nacional Autónoma de México e Instituto Nacional de Medicina Genómica, Mexico City 04510, Mexico.
  • Acuna-Alonso V; National Institute of Anthropology and History, Mexico City 4510, Mexico.
  • Gallo C; Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima 15102, Peru.
  • Poletti G; Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima 15102, Peru.
  • Bedoya G; Genética Molecular (GENMOL), Universidad de Antioquia, Medellín 5001000, Colombia.
  • Rothhammer F; Instituto de Alta Investigación, Universidad de Tarapacá, Arica 1000009, Chile; Programa de Genetica Humana, ICBM, Facultad de Medicina, Universidad de Chile, Santiago 1027, Chile.
  • Ito S; Institute for Melanin Chemistry, Fujita Health University, Toyoake, Aichi 470-1192, Japan.
  • Schiaffino MV; Internal Medicine, Diabetes and Endocrinology Unit, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy.
  • Chao LH; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Kleinstiver BP; Center for Genomic Medicine and Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.
  • Tishkoff S; Departments of Genetics and Biology, University of Pennsylvania, Philadelphia, PA, USA.
  • Zon LI; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and the Howard Hughes Medical Institute, Boston, MA 02115, USA.
  • Nijsten T; Department of Dermatology, Erasmus Medical Center, 3015 Rotterdam, the Netherlands.
Cell ; 184(16): 4268-4283.e20, 2021 08 05.
Article em En | MEDLINE | ID: mdl-34233163
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article