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A modular protein subunit vaccine candidate produced in yeast confers protection against SARS-CoV-2 in non-human primates.
Dalvie, Neil C; Tostanoski, Lisa H; Rodriguez-Aponte, Sergio A; Kaur, Kawaljit; Bajoria, Sakshi; Kumru, Ozan S; Martinot, Amanda J; Chandrashekar, Abishek; McMahan, Katherine; Mercado, Noe B; Yu, Jingyou; Chang, Aiquan; Giffin, Victoria M; Nampanya, Felix; Patel, Shivani; Bowman, Lesley; Naranjo, Christopher A; Yun, Dongsoo; Flinchbaugh, Zach; Pessaint, Laurent; Brown, Renita; Velasco, Jason; Teow, Elyse; Cook, Anthony; Andersen, Hanne; Lewis, Mark G; Camp, Danielle L; Silverman, Judith Maxwell; Kleanthous, Harry; Joshi, Sangeeta B; Volkin, David B; Biswas, Sumi; Love, J Christopher; Barouch, Dan H.
Afiliação
  • Dalvie NC; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
  • Tostanoski LH; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
  • Rodriguez-Aponte SA; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Kaur K; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
  • Bajoria S; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
  • Kumru OS; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, Kansas, 66047, USA.
  • Martinot AJ; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, Kansas, 66047, USA.
  • Chandrashekar A; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, Kansas, 66047, USA.
  • McMahan K; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Mercado NB; Departments of Infectious Diseases and Global Health and Comparative Pathobiology, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA.
  • Yu J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Chang A; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Giffin VM; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Nampanya F; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Patel S; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Bowman L; Harvard Medical School, Boston, MA 02115, USA.
  • Naranjo CA; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Yun D; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Flinchbaugh Z; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Pessaint L; SpyBiotech Limited, Oxford Business Park North, Oxford, OX4 2JZ, United Kingdom.
  • Brown R; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
  • Velasco J; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
  • Teow E; Bioqual, Rockville, MD 20852, USA.
  • Cook A; Bioqual, Rockville, MD 20852, USA.
  • Andersen H; Bioqual, Rockville, MD 20852, USA.
  • Lewis MG; Bioqual, Rockville, MD 20852, USA.
  • Camp DL; Bioqual, Rockville, MD 20852, USA.
  • Silverman JM; Bioqual, Rockville, MD 20852, USA.
  • Kleanthous H; Bioqual, Rockville, MD 20852, USA.
  • Joshi SB; Bioqual, Rockville, MD 20852, USA.
  • Volkin DB; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
  • Biswas S; Bill & Melinda Gates Medical Research Institute, Cambridge, MA 02139, USA.
  • Love JC; Bill&Melinda Gates Foundation, Seattle, WA 98109, USA.
  • Barouch DH; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, Kansas, 66047, USA.
bioRxiv ; 2021 Jul 14.
Article em En | MEDLINE | ID: mdl-34282417
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article