Neural-ODE for pharmacokinetics modeling and its advantage to alternative machine learning models in predicting new dosing regimens.

Lu, James; Deng, Kaiwen; Zhang, Xinyuan; Liu, Gengbo; Guan, Yuanfang

Lu, James; Deng, Kaiwen; Zhang, Xinyuan; Liu, Gengbo; Guan, Yuanfang.

Afiliação

Lu J; Modeling & Simulation/Clinical Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
Deng K; Ann Arbor Algorithms Inc, 3001 Plymouth Road, Ann Arbor, MI 48105, USA.
Zhang X; Ann Arbor Algorithms Inc, 3001 Plymouth Road, Ann Arbor, MI 48105, USA.
Liu G; Modeling & Simulation/Clinical Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
Guan Y; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.

iScience ; 24(7): 102804, 2021 Jul 23.

Article em En | MEDLINE | ID: mdl-34308294

Palavras-chave

Bioinformatics; Machine learning; Pharmacoinformatics; Pharmacological parameters

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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