Differential Response of MDA-MB-231 and MCF-7 Breast Cancer Cells to In Vitro Inhibition with CTLA-4 and PD-1 through Cancer-Immune Cells Modified Interactions.

Grubczak, Kamil; Kretowska-Grunwald, Anna; Groth, Dawid; Poplawska, Izabela; Eljaszewicz, Andrzej; Bolkun, Lukasz; Starosz, Aleksandra; Holl, Jordan M; Mysliwiec, Marta; Kruszewska, Joanna; Wojtukiewicz, Marek Z; Moniuszko, Marcin

Grubczak, Kamil; Kretowska-Grunwald, Anna; Groth, Dawid; Poplawska, Izabela; Eljaszewicz, Andrzej; Bolkun, Lukasz; Starosz, Aleksandra; Holl, Jordan M; Mysliwiec, Marta; Kruszewska, Joanna; Wojtukiewicz, Marek Z; Moniuszko, Marcin.

Afiliação

Grubczak K; Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Jerzego Waszyngtona 13, 15-269 Bialystok, Poland.
Kretowska-Grunwald A; Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Jerzego Waszyngtona 13, 15-269 Bialystok, Poland.
Groth D; Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Jerzego Waszyngtona 13, 15-269 Bialystok, Poland.
Poplawska I; Department of Medical Pathomorphology, Medical University of Bialystok, Jerzego Waszyngtona 13, 15-269 Bialystok, Poland.
Eljaszewicz A; Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Jerzego Waszyngtona 13, 15-269 Bialystok, Poland.
Bolkun L; Department of Haematology, Medical University of Bialystok, M. Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland.
Starosz A; Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Jerzego Waszyngtona 13, 15-269 Bialystok, Poland.
Holl JM; Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Jerzego Waszyngtona 13, 15-269 Bialystok, Poland.
Mysliwiec M; Department of Oncology, Medical University of Bialystok, Ogrodowa 12, 15-027 Bialystok, Poland.
Kruszewska J; Department of Oncology, Medical University of Bialystok, Ogrodowa 12, 15-027 Bialystok, Poland.
Wojtukiewicz MZ; Department of Oncology, Medical University of Bialystok, Ogrodowa 12, 15-027 Bialystok, Poland.
Moniuszko M; Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Jerzego Waszyngtona 13, 15-269 Bialystok, Poland.

Cells ; 10(8)2021 08 10.

Article em En | MEDLINE | ID: mdl-34440813

Assuntos

Antígeno CTLA-4/imunologia; Leucócitos Mononucleares/metabolismo; Receptor de Morte Celular Programada 1/imunologia; Adulto; Anticorpos/imunologia; Antígeno B7-1/metabolismo; Neoplasias da Mama/metabolismo; Neoplasias da Mama/patologia; Antígeno CTLA-4/metabolismo; Pontos de Checagem do Ciclo Celular; Linhagem Celular Tumoral; Proliferação de Células; Técnicas de Cocultura; Feminino; Granzimas/metabolismo; Humanos; Interferon gama/metabolismo; Interleucina-10/metabolismo; Leucócitos Mononucleares/citologia; Leucócitos Mononucleares/imunologia; Células MCF-7; Perforina/metabolismo; Receptor de Morte Celular Programada 1/metabolismo

Palavras-chave

CTLA-4; PD-1; anti-tumor immunity; breast cancer; immune checkpoint inhibitors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Adult / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Adult / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article