Metabolite profiling, anti-inflammatory, analgesic potentials of edible herb Colocasia gigantea and molecular docking study against COX-II enzyme.

Zilani, Md Nazmul Hasan; Islam, Md Aminul; Biswas, Partha; Anisuzzman, Md; Hossain, Hemayet; Shilpi, Jamil A; Hasan, Md Nazmul; Hossain, Md Golam

Zilani, Md Nazmul Hasan; Islam, Md Aminul; Biswas, Partha; Anisuzzman, Md; Hossain, Hemayet; Shilpi, Jamil A; Hasan, Md Nazmul; Hossain, Md Golam.

Afiliação

Zilani MNH; Department of Pharmacy, Jashore University of Science and Technology, Jashore, 7408, Bangladesh. Electronic address: mnhzilani09@gmail.com.
Islam MA; Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh. Electronic address: aminuljust1996@gmail.com.
Biswas P; Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh. Electronic address: partha_160626@just.edu.bd.
Anisuzzman M; Pharmacy Discipline, Life Science School, Khulna University, Khulna, 9208, Bangladesh; Sydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2006, Australia. Electronic address: manisuzzman1984@gmail.com.
Hossain H; BCSIR Laboratories & IFST, Bangladesh Council of Scientific and Industrial Research (BCSIR), Dhaka, 1205, Bangladesh. Electronic address: hemayethossain02@yahoo.com.
Shilpi JA; Pharmacy Discipline, Life Science School, Khulna University, Khulna, 9208, Bangladesh. Electronic address: jamilshilpi@yahoo.com.
Hasan MN; Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh. Electronic address: mnhasan1978@gmail.com.
Hossain MG; Pharmacy Discipline, Life Science School, Khulna University, Khulna, 9208, Bangladesh. Electronic address: ghossain72@yahoo.com.

J Ethnopharmacol ; 281: 114577, 2021 Dec 05.

Article em En | MEDLINE | ID: mdl-34464698

Assuntos

Analgésicos/farmacologia; Anti-Inflamatórios/farmacologia; Colocasia/química; Fitoterapia; Plantas Comestíveis/química; Analgésicos/química; Animais; Anti-Inflamatórios/química; Biomarcadores; Ciclo-Oxigenase 2/química; Ciclo-Oxigenase 2/metabolismo; Relação Dose-Resposta a Droga; Regulação Enzimológica da Expressão Gênica/efeitos dos fármacos; Humanos; Camundongos; Modelos Moleculares; Simulação de Acoplamento Molecular; Estrutura Molecular; Compostos Fitoquímicos/efeitos adversos; Compostos Fitoquímicos/química; Compostos Fitoquímicos/farmacocinética; Extratos Vegetais/química; Extratos Vegetais/farmacologia; Conformação Proteica; Testes de Toxicidade

Palavras-chave

9,12-Octadecadienoic acid; Cyclooxygenase-II; GCMS; HPLC; Molecular docking; Trans-Cinnamic acid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article