Defective myelination in an RNA polymerase III mutant leukodystrophic mouse.

Merheb, Emilio; Cui, Min-Hui; DuBois, Juwen C; Branch, Craig A; Gulinello, Maria; Shafit-Zagardo, Bridget; Moir, Robyn D; Willis, Ian M

Merheb, Emilio; Cui, Min-Hui; DuBois, Juwen C; Branch, Craig A; Gulinello, Maria; Shafit-Zagardo, Bridget; Moir, Robyn D; Willis, Ian M.

Afiliação

Merheb E; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461.
Cui MH; Department of Radiology, Albert Einstein College of Medicine, Bronx, NY 10461.
DuBois JC; Gruss Magnetic Resonance Research Center, Albert Einstein College of Medicine, Bronx, NY 10461.
Branch CA; Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461.
Gulinello M; Department of Radiology, Albert Einstein College of Medicine, Bronx, NY 10461.
Shafit-Zagardo B; Gruss Magnetic Resonance Research Center, Albert Einstein College of Medicine, Bronx, NY 10461.
Moir RD; Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461.
Willis IM; Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461.

Proc Natl Acad Sci U S A ; 118(40)2021 10 05.

Article em En | MEDLINE | ID: mdl-34583988

Assuntos

Doenças Desmielinizantes/fisiopatologia; Mutação; RNA Polimerase III/genética; Animais; Doenças Desmielinizantes/genética; Crescimento; Humanos; Masculino; Camundongos; Camundongos Mutantes

Palavras-chave

RNA polymerase III; hypomyelination; leukodystrophy; oligodendrocyte

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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