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Remdesivir triphosphate blocks DNA synthesis and increases exonucleolysis by the replicative mitochondrial DNA polymerase, Pol γ.
Ciesielska, Elena J; Kim, Shalom; Bisimwa, Hyacintha-Ghislaine M; Grier, Cody; Rahman, Md Mostafijur; Young, Carolyn K J; Young, Matthew J; Oliveira, Marcos T; Ciesielski, Grzegorz L.
Afiliação
  • Ciesielska EJ; Department of Chemistry, Auburn University at Montgomery, Montgomery, AL 36117, United States.
  • Kim S; Department of Chemistry, Auburn University at Montgomery, Montgomery, AL 36117, United States.
  • Bisimwa HM; Department of Chemistry, Auburn University at Montgomery, Montgomery, AL 36117, United States.
  • Grier C; Department of Chemistry, Auburn University at Montgomery, Montgomery, AL 36117, United States.
  • Rahman MM; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901, United States.
  • Young CKJ; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901, United States.
  • Young MJ; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901, United States.
  • Oliveira MT; Departamento de Tecnologia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista "Júlio de Mesquita Filho", Jaboticabal, SP, Brazil.
  • Ciesielski GL; Department of Chemistry, Auburn University at Montgomery, Montgomery, AL 36117, United States. Electronic address: gciesiel@aum.edu.
Mitochondrion ; 61: 147-158, 2021 11.
Article em En | MEDLINE | ID: mdl-34619353

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article