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Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ).
Degtjarik, Oksana; Golovenko, Dmitrij; Diskin-Posner, Yael; Abrahmsén, Lars; Rozenberg, Haim; Shakked, Zippora.
Afiliação
  • Degtjarik O; Department of Chemical and Structural Biology, Weizmann Institute of Science, 76100, Rehovot, Israel.
  • Golovenko D; Department of Chemical and Structural Biology, Weizmann Institute of Science, 76100, Rehovot, Israel.
  • Diskin-Posner Y; University of Massachusetts Medical School, RNA Therapeutics Institute, Worcester, MA, 01605, USA.
  • Abrahmsén L; Department of Chemical Research Support, Weizmann Institute of Science, 76100, Rehovot, Israel.
  • Rozenberg H; Aprea Therapeutics AB, 17165, Solna, Sweden.
  • Shakked Z; Department of Chemical and Structural Biology, Weizmann Institute of Science, 76100, Rehovot, Israel. haim.rozenberg@weizmann.ac.il.
Nat Commun ; 12(1): 7057, 2021 12 03.
Article em En | MEDLINE | ID: mdl-34862374
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article