TNF-&#945;-induced E3 ligase, TRIM15 inhibits TNF-&#945;-regulated NF-&#954;B pathway by promoting turnover of K63 linked ubiquitination of TAK1.

Roy, Milton; Singh, Kritarth; Shinde, Anjali; Singh, Jyoti; Mane, Minal; Bedekar, Sawani; Tailor, Yamini; Gohel, Dhruv; Vasiyani, Hitesh; Currim, Fatema; Singh, Rajesh

TNF-α-induced E3 ligase, TRIM15 inhibits TNF-α-regulated NF-κB pathway by promoting turnover of K63 linked ubiquitination of TAK1.

Roy, Milton; Singh, Kritarth; Shinde, Anjali; Singh, Jyoti; Mane, Minal; Bedekar, Sawani; Tailor, Yamini; Gohel, Dhruv; Vasiyani, Hitesh; Currim, Fatema; Singh, Rajesh.

Afiliação

Roy M; Department of Biochemistry, Faculty of Science, The MS University of Baroda, Vadodara, Gujarat 390002, India.
Singh K; Department of Biochemistry, Faculty of Science, The MS University of Baroda, Vadodara, Gujarat 390002, India.
Shinde A; Department of Biochemistry, Faculty of Science, The MS University of Baroda, Vadodara, Gujarat 390002, India.
Singh J; Department of Biochemistry, Faculty of Science, The MS University of Baroda, Vadodara, Gujarat 390002, India.
Mane M; Department of Biochemistry, Faculty of Science, The MS University of Baroda, Vadodara, Gujarat 390002, India.
Bedekar S; Department of Biochemistry, Faculty of Science, The MS University of Baroda, Vadodara, Gujarat 390002, India.
Tailor Y; Department of Biochemistry, Faculty of Science, The MS University of Baroda, Vadodara, Gujarat 390002, India.
Gohel D; Department of Biochemistry, Faculty of Science, The MS University of Baroda, Vadodara, Gujarat 390002, India.
Vasiyani H; Department of Biochemistry, Faculty of Science, The MS University of Baroda, Vadodara, Gujarat 390002, India.
Currim F; Department of Biochemistry, Faculty of Science, The MS University of Baroda, Vadodara, Gujarat 390002, India.
Singh R; Department of Biochemistry, Faculty of Science, The MS University of Baroda, Vadodara, Gujarat 390002, India. Electronic address: singhraj1975@gmail.com.

Cell Signal ; 91: 110210, 2022 03.

Article em En | MEDLINE | ID: mdl-34871740

Assuntos

NF-kappa B; Ubiquitina-Proteína Ligases; Proteínas de Transporte/metabolismo; Humanos; NF-kappa B/metabolismo; Proteínas do Tecido Nervoso/metabolismo; Transdução de Sinais; Fator de Necrose Tumoral alfa/metabolismo; Ubiquitina-Proteína Ligases/metabolismo; Ubiquitinação

Palavras-chave

Functional antagonism; NF-κB; TNF-α; TRIM15; TRIM8; Ubiquitination

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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