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First-in-human phase 1 dose-escalation study of CAN04, a first-in-class interleukin-1 receptor accessory protein (IL1RAP) antibody in patients with solid tumours.
Robbrecht, Debbie; Jungels, Christiane; Sorensen, Morten Mau; Spanggaard, Iben; Eskens, Ferry; Fretland, Signe Ø; Guren, Tormod Kyrre; Aftimos, Philippe; Liberg, David; Svedman, Christer; Thorsson, Lars; Steeghs, Neeltje; Awada, Ahmad.
Afiliação
  • Robbrecht D; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. d.robbrecht@erasmusmc.nl.
  • Jungels C; Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Sorensen MM; Department of Oncology, Rigshospitalet, Copenhagen, Denmark.
  • Spanggaard I; Department of Oncology, Rigshospitalet, Copenhagen, Denmark.
  • Eskens F; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Fretland SØ; Department of Oncology, Oslo University Hospital, Oslo, Norway.
  • Guren TK; Department of Oncology, Oslo University Hospital, Oslo, Norway.
  • Aftimos P; Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Liberg D; Cantargia, Lund, Sweden.
  • Svedman C; Cantargia, Lund, Sweden.
  • Thorsson L; Cantargia, Lund, Sweden.
  • Steeghs N; Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Awada A; Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
Br J Cancer ; 126(7): 1010-1017, 2022 04.
Article em En | MEDLINE | ID: mdl-34903842
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article