A study to predict fracture risk using bone mineral density and FRAX score in patients on chronic maintenance haemodialysis.

ABSTRACT

Introduction: Disturbances in mineral and bone metabolism are prevalent in chronic kidney disease (CKD) and are important causes of morbidity also their diagnosis often delayed and require a spectrum of investigations. The current study attempts to predict and correlate, the fracture risk using simple tools like BMD and FRAX (Fracture Risk Assessment Tool) score in CKD patients. Methods: A cross-sectional study among 50 CKD patients age more that 40 years attending OPD (Out Patient Department) at a tertiary care Hospital in north India. Results: There is a negative correlation between BMD (NOF) and FRAX score for hip fracture risk and major osteoporotic fracture risk. Conclusion: The 10-year fracture risk in these patients, as predicted by FRAX score using FRAX (Indian) calculator, was significantly higher in CKD patients. Recommendation FRAX can be useful tool for early screening of fracture risk in such situations for timely interventions.