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Secondary resistance to idelalisib is characterized by upregulation of IGF1R rather than by MAPK/ERK pathway mutations.
Tausch, Eugen; Ljungström, Viktor; Agathangelidis, Andreas; Zapatka, Marc; Scarfò, Lydia; Jebaraj, Billy Michael Chelliah; Yosifov, Deyan Y; Müller, Annika; Munugalavadla, Veerendra; Degenhardt, Jeremiah D; Ghia, Paolo; Rosenquist, Richard; Stilgenbauer, Stephan.
Afiliação
  • Tausch E; Division of Chronic Lymphocytic Leukemia, Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Ljungström V; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Agathangelidis A; Università Vita-Salute San Raffaele and Ospedale San Raffaele, Milan, Italy.
  • Zapatka M; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.
  • Scarfò L; German Cancer Research Center, Heidelberg, Germany.
  • Jebaraj BMC; Università Vita-Salute San Raffaele and Ospedale San Raffaele, Milan, Italy.
  • Yosifov DY; Division of Chronic Lymphocytic Leukemia, Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Müller A; Division of Chronic Lymphocytic Leukemia, Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Munugalavadla V; German Cancer Research Center, Heidelberg, Germany.
  • Degenhardt JD; Division of Chronic Lymphocytic Leukemia, Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Ghia P; Translational Medicine, Hematology Research and Development, AstraZeneca, South San Francisco, CA.
  • Rosenquist R; Research and Development, Maverick Therapeutics, Brisbane, CA.
  • Stilgenbauer S; Università Vita-Salute San Raffaele and Ospedale San Raffaele, Milan, Italy.
Blood ; 139(22): 3340-3344, 2022 06 02.
Article em En | MEDLINE | ID: mdl-35377939

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article