Mediation of the behavioral effects of ketamine and (2R,6R)-hydroxynorketamine in mice by kappa opioid receptors.

Wulf, Hildegard A; Browne, Caroline A; Zarate, Carlos A; Lucki, Irwin

Wulf, Hildegard A; Browne, Caroline A; Zarate, Carlos A; Lucki, Irwin.

Afiliação

Wulf HA; Department of Pharmacology and Molecular Therapeutics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Browne CA; Department of Pharmacology and Molecular Therapeutics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA. caroline.browne.ctr@usuhs.edu.
Zarate CA; National Institute on Mental Health, MD, 20814, Bethesda, USA.
Lucki I; Department of Pharmacology and Molecular Therapeutics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA. irwin.lucki@usush.edu.

Psychopharmacology (Berl) ; 239(7): 2309-2316, 2022 Jul.

Article em En | MEDLINE | ID: mdl-35459958

Assuntos

Comportamento Animal; Ketamina; Naltrexona; Animais; Comportamento Animal/efeitos dos fármacos; Transtorno Depressivo Maior; Humanos; Ketamina/análogos & derivados; Ketamina/farmacologia; Camundongos; Naltrexona/farmacologia; Receptores Opioides kappa

Palavras-chave

(2R,6R)-Hydroxynorketamine; Depression; HNK; Kappa opioid receptor; Ketamine; LY2444296; MDD; Naltrexone; Repeated (2R,6R)-hydroxynorketamine; Repeated HNK; Repeated ketamine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article