Pentosan polysulfate induces low-level persistent prion infection keeping measurable seeding activity without PrP-res detection in Fukuoka-1 infected cell cultures.

Takatsuki, Hanae; Imamura, Morikazu; Mori, Tsuyoshi; Atarashi, Ryuichiro

Pentosan polysulfate induces low-level persistent prion infection keeping measurable seeding activity without PrP-res detection in Fukuoka-1 infected cell cultures.

Takatsuki, Hanae; Imamura, Morikazu; Mori, Tsuyoshi; Atarashi, Ryuichiro.

Afiliação

Takatsuki H; Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan.
Imamura M; Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan.
Mori T; Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan.
Atarashi R; Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan. ryuichiro_atarashi@med.miyazaki-u.ac.jp.

Sci Rep ; 12(1): 7923, 2022 05 13.

Article em En | MEDLINE | ID: mdl-35562591

Assuntos

Doenças Priônicas; Príons; Animais; Camundongos; Poliéster Sulfúrico de Pentosana/farmacologia; Poliéster Sulfúrico de Pentosana/uso terapêutico; Proteínas PrPSc/metabolismo; Doenças Priônicas/tratamento farmacológico; Doenças Priônicas/metabolismo; Proteínas Priônicas/metabolismo; Príons/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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