Cytotoxic nortriterpenoids from the barks of Juglans cathayensis.
J Asian Nat Prod Res
; 25(2): 111-117, 2023 Feb.
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em En
| MEDLINE
| ID: mdl-35579284
ABSTRACT
A chemical study of 90% ethanol extract of the barks of Juglans cathayensis resulted in the isolation of three new nortriterpenoids, jugcathenoids A-C (1-3). The structures of the new compounds were elucidated by spectroscopic analysis (NMR, IR, UV, and MS). The isolated nortriterpenoids were tested in vitro for cytotoxic activities against 6 pancreatic cell lines. As a result, compounds 1-3 exhibited some cytotoxic activities against all the tested tumor cell lines with IC50 values less than 50 µM.
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01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2023
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Article